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Section 10 Index

Index to Course Material

BIRKBECK'S PROTEIN DOMAIN DATABASE

Domain boundaries of a largely non-redundant set of proteins for which structures have been submitted in the Brookhaven Protein Data Bank (Bernstein F.C. et al. & Tasumi, M., J. Mol. Biol. 112, 535-542 (1977)). The non-homologous dataserver at EMBL (by Hobohm, U., Scharf, M., Schneider, R. & Sander, C., Protein Science , 1, 409-417 (1992)) has been used as a guideline to obtain this dataset.

Domains have been identified based on the clustering of secondary structures. For details of the method you may also see the papers

( An automatic method involving cluster analysis of secondary structures for the identification of domains in proteins by Sowdhamini, R. and Blundell, T.L. Protein Science , 4 , 506-520 (1995).

A database of globular protein structural domains : Clustering of representative family members into similar folds by Sowdhamini, R., Rufino, S.D. & Blundell, T.L. Folding and Design (in press). This algorithm has presently been applied to 436 protein chains. This table will be periodically updated (currently 14th Feb. 1996).


Table 1 : LIST OF PROTEIN DOMAINS USED FOR THE ANALYSIS.

_______________________________________________________________________________________________________________________________________________________
PDB  Ch.  No. of    D             Domain boundaries                                 Helix content            Protein name               Helix content
code      domains    f                                                               for domains                                        for full chain
_______________________________________________________________________________________________________________________________________________________
119l        2     1.32657   85 -155;                                                  1.00 a     Lysozyme (Bacteriophage T4)
                           3 - 80;                                                    0.75 a                                          
153l        2m    1.10290   18 - 74;169 -182;                                         1.00 a     Lysozyme (Goose)                          0.96 a    
                          90 -149;                                                    0.90 a                                          
1aaj        2m    1.06212    3 -  4; 34 - 38; 56 - 68; 86 -105;                       0.00 b     Amicyanin                                 0.00 b    
                          11 - 30; 42 - 47; 76 - 82;                                  0.00 b                                          
1aak        2c    1.29120    8 -114;                                                  0.46 ab    Ubiquitin Conjugating Enzyme          
                          (124 -147;)
1abr  B     2     1.59486  145 -265;                                                  0.00 b     Abrin-a                                
                          15 -138;                                                    0.00 b                                          
1add        2m    1.13004   11 - 17; 58 - 61; 95 -102;147 -350;                       0.67 ab    Adenosine Deaminase                       0.76 a,ab 
                          24 - 50; 69 - 92;126 -144;                                  1.00 a                                          
1ads        2m    1.08695    3 -209;244 -273;                                         0.70 ab    Aldose Reductase                          0.74 ab   
                         231 -240;282 -289;                                           1.00 a                                          
1aep        1                                                                         1.00 a     Apolipophorin III                       
1afp        1                                                                         0.00 b     Antifungal Protein                    
1agx        2     1.52753    3 -191;                                                  0.53 ab    Glutaminase-asparaginase              
                         218 -328;                                                    0.68 ab                                         
1alk  A     2     1.12236   30 - 50; 80 -258;299 -323;335 -367;417 -446;              0.62 ab    Alkaline Phosphatase                  
                          55 - 65;268 -288;325 -331;375 -402;                         0.51 ab                                         
1amp        1                                                                         0.67 ab    Aminopeptidase 
1amy        2c    1.12078    3 - 88;154 -402;                                         0.63 ab    Alpha-1,4 Glycan-4-glucanohydrolase 
                           (97 -106;)  
1aor  A     4     1.29249    7 -204;520 -541;593 -599;                                0.55 ab    Aldehyde Ferredoxin Oxidoreductase 
                         344 -491;545 -583;                                           0.96 a
                         232 -340;                                                    0.75 ab 
                         214 -230;503 -514;                                           1.00 a 
1aoz  A     3     1.35386  149 -155;345 -545;                                         0.28 ab    Ascorbate Oxidase                     
                         135 -144;169 -327;                                           0.10 b                                          
                           3 -122;                                                    0.00 b                                          
1apl  C     1                                                                         1.00 a     Mat Alpha2 Homeodomain                
1apm  E     3c+   1.37148   43 -121;162 -163;189 -190;                                0.31 ab    c-AMP-dependent Protein Kinase        
                               128 -159;172 -182;218 -233;263 -307;                   0.91 a                                          
                        (207-210; 243-252;)
1apv  E     3     1.44151  192 -303;                                                  0.18 b     Acid Proteinase                           
                          17 -144;                                                    0.23 ab ,b                                      
                           4 - 10;152 -183;306 -321;                                  0.00 b                                          
1arb        2     1.10574    8 -  9;130 -262;                                         0.19 b     Achromobacter Protease I              
                          25 -119;                                                    0.12 b                                          
1ars        2+    1.27450   51 -159;170 -310;                                         0.70 ab    Aspartate Aminotransferase            
                          18 - 34;161 -168;313 -405;                                  0.82 a                                          
1ash        2m    1.16251    1 - 10; 82 -144;                                         1.00 a     Hemoglobin                                1.00 a    
                          20 - 77;                                                    1.00 a                                          
1asz  A     3     1.60920  242 -269;303 -484;522 -537;                                0.65 ab    Aspartyl Trna Synthetase              
                          75 -238;                                                    0.34 ab                                         
                         275 -298;489 -513;                                           0.82 a                                          
1atn  A     4     1.61198  136 -177;273 -329;                                         0.57 ab    Deoxyribonuclease I                        
                          15 - 90;                                                    0.43 ab                                         
                           7 - 11;102 -135;337 -370;                                  0.67 ab                                         
                         181 -261;                                                    0.85 a                                          
1atx        1                                                                         0.00 b     ATX Ia                                
1aty        1                                                                         1.00 a     F1fo Atp Synthase Subunit C            
1aya  A     2m    1.28353   13 - 55;100 -101;                                         0.32 ab    Tyrosine Phosphatase                      0.44 ab   
                          57 - 83;                                                    0.71 ab                                         
1baa        2     1.36096   31 - 39;112 -159;                                         0.88 a     Endochitinase                         
                           8 - 14; 51 - 67;168 -171;191 -226;                         1.00 a                                          
1bab  B     2m    1.29983   20 - 74;101 -118;                                         1.00 a     Hemoglobin                                1.00 a    
                           5 - 15;124 -142;                                           1.00 a                                          
1bar  A     1                                                                         0.00 b     Acidic Fibroblast Growth Factor           
1bbl  -     1                                                                         1.00 a     Dihydrolipoamide Succinyltransferase      
1bbo  -     1                                                                         0.83 a     Human Enhancer-binding Protein           
1bbp  A     1                                                                         0.17 b     Bilin Binding Protein                 
1bbt  1     1                                                                         0.18 b                                          
1bbt  2     1                                                                         0.08 b                                          
1bcf  A     2m    1.25906   83 -144;                                                  1.00 a     Bacterioferritin                          1.00 a    
                           5 - 64;                                                    1.00 a                                          
1bct        1                                                                         1.00 a     Bacteriorhodopsin                     
1bet        2m    1.17807   17 - 38; 53 -114;                                         0.00 b     Beta-nerve Growth Factor                  0.00 b    
                          41 - 50;                                                    0.00 b                                          
1bge  B     2m    1.07854   12 - 40; 72 -124;                                         1.00 a     Granulocyte Colony-stimulating Factor     1.00 a    
                          49 - 55;144 -169;                                           1.00 a                                          
1bmd  A     2     1.26825    4 -153;242 -298;                                         0.61 ab    Malate Dehydrogenase                       
                         156 -237;306 -328;                                           0.83 a                                          
1bpb        3     1.53733  150 -273;                                                  0.56 ab    Dna Polymerase Beta                       
                         276 -321;                                                    0.80 ab                                         
                          94 -141;                                                    1.00 a                                          
1bsa  A     1                                                                         0.44 ab    Barnase                                            
1bw4        1                                                                         0.32 ab    Barwin, Basic Barley Seed Protein     
1c5a        1                                                                         1.00 a     Des-arg==74==-complement C5a          
1cau  A     3m    1.45221   56 - 93;107 -114;137 -140;157 -164;                       0.00 b     Canavalin                                 0.15 bb
                            97 -104 ;116 -133 ;145 -150 ;174 -176 ;                   0.00 b
                           192 -207 ;                                                 1.00 a
1cau  B     2c    1.19232  258 -378;418 -420;                                         0.08 b     Canavalin                             
                          (392 -411;)
1cbn  -     1                                                                         0.80 a     Crambin                                   
1ccf        2m    1.96045   76 - 84;                                                  0.00 b     Coagulation Factor X                      0.00 b    
                          60 - 71;                                                    0.00 b                                          
1ccr        2m    1.32376   58 - 82;                                                  1.00 a     Cytochrome c                              1.00 a    
                          11 - 21; 96 -109;                                           1.00 a                                          
1cde        2+    1.18110    2 -108;                                                  0.59 ab    Phosphoribosylglycinamide Formyltransferase
                         131 -202;                                                    0.48 ab                                         
1cdg        4*              17 - 406;                                                 0.69 ab    Cyclodextrin Glycosyltransferase                         
                           408 - 493;                                                 0.00 b
                           500 - 581;                                                 0.00 b
                           586 - 683;                                                 0.00 b
1cdt  A     2m    1.08645   20 - 54;                                                  0.00 b     Cardiotoxin V4II                          0.00 b    
                           2 - 13;                                                    0.00 b                                          
1cel  A     3     1.34787   13 - 34; 78 -147;212 -228;274 -312;359 -425;              0.12 b     1,4-beta-d-glucan Cellobiohydrolase I 
                           2 -  3; 41 - 73;182 -209;236 -239;                         0.20 b                                          
                         316 -356;                                                    0.80 b                                          
1cew  I     1                                                                         0.30 ab    Cystatin                                  
1cfb        2     1.88515  721 -809;                                                  0.00 b     Drosophila Neuroglian                  
                         619 -708;                                                    0.00 b                                          
1chl        1                                                                         0.57 ab    Chlorotoxin                               
1chm  A     3     1.48344    6 -156;                                                  0.66 ab    Creatine Amidinohydrolase             
                         219 -251;261 -311;360 -374;396 -401;                         0.56 ab                                         
                         161 -209;253 -258;329 -357;377 -388;                         0.66 ab                                         
1chr  A     3+    1.40620  135 -295;                                                  0.69 ab    Chloromuconate Cycloisomerase             0.75 ab   
                           8 -116;360 -365;                                           0.89 a                                          
                         120 -133;303 -347;                                           0.61 ab                                         
1cid        2     1.31194    4 -110;                                                  0.00 b     Cd4                                   
                         116 -176;                                                    0.00 b                                          
1cks  A     1                                                                         0.60 ab    Cyclin-dependent Kinase                  
1cmb  A     1                                                                         0.91 a     Met Apo-repressor                     
1cob  A     1                                                                         0.00 b     Superoxide Dismutase                  
1col  A     2m    1.07425   76 -164;                                                  1.00 a     Colicin A                                 1.00 a    
                           8 - 67;169 -198;                                           1.00 a                                          
1cpc  A     2c    1.11350   48 -172;                                                  1.00 a     C-phycocyanin                         
                            (4-46;)
1cpt        4     1.50628    9 - 91;318 -345;                                         0.65 ab    Cytochrome P450                  
                         150 -156;287 -295;398 -427;                                  0.39 ab                                         
                         130 -145;161 -185;254 -285;300 -311;380 -394;                1.00 a                                          
                         109 -126;208 -244;                                           1.00 a                                          
1cpy        3     1.36779   46 - 50; 89 - 91;140 -175;317 -415;                       0.56 ab    Carboxypeptidase                      
                          18 - 35; 59 - 79;103 -129;271 -287;                         0.61 ab                                         
                         181 -251;300 -307;                                           1.00 a                                          
1crl        4     1.34743  136 -144;210 -220;236 -240;319 -338;416 -513;              0.69 ab    Lipase (Triacylglycerol Hydrolase)    
                           3 - 27; 99 -120;150 -154;177 -208;227 -232;                0.25 ab                                         
                          73 - 90;159 -172;253 -291;                                  1.00 a                                          
                         343 -414;519 -526;                                           1.00 a                                          
1cse  I     1                                                                         0.34 ab    Subtilisin Carlsberg 
1csk  A     1                                                                         0.00 b     C-src Kinase                          
1csp        1                                                                         0.00 b     Major Cold Shock Protein              
1ctm        2     1.46004    2 -154;235 -245;                                         0.20 b     Cytochrome F                          
                         177 -221;                                                    0.00 b                                          
1ctn        3     1.66415  159 -192;267 -442;518 -555;                                0.62 ab    Chitinase A                           
                          30 -131;210 -262;                                           0.32 ab                                         
                         444 -514;                                                    0.21 ab ,b                                      
1ctt        3     1.57723   32 - 33; 49 -160;                                         0.60 ab    Cytidine Deaminase                          
                         190 -292;                                                    0.57 ab                                         
                           6 - 20; 35 - 44;                                           1.00 a                                          
1cus        1                                                                         0.70 ab    Cutinase                              
1d66  A     1                                                                         1.00 a     Gal4                                      
1ddt        3     1.97436  389 -534;                                                  0.00 b     Diphtheria Toxin                      
                         206 -376;                                                    0.97 a                                          
                          12 -182;                                                    0.40 ab                                         
1dec        2m    1.07675   27 - 38;                                                  0.00 b     Decorsin                                  0.00 b    
                          15 - 22;                                                    0.00 b                                          
1dfn  A     1                                                                         0.00 b     Defensin HNP-3                        
1dge        3*    1.42128   62 -209;225 -323;                                         0.76 ab    Dialkylglycine Decarboxylase              
                          29 - 53;326 -432;                                           0.62 ab 
                          212 -220;                                                   0.00 a
1dhr        3m    1.05896  172 -238;                                                  0.42 ab    Dihydropteridine Reductase                0.61 ab   
                           8 - 81;122 -131;                                           0.47 ab                                         
                          96 -121;144 -160;                                           1.00 a                                          
1dlc        3     1.60162  295 -296;503 -643;                                         0.00 b     Delta-endotoxin Cryiiia               
                         259 -275;302 -451;471 -495;                                  0.18 b                                          
                          63 -253;277 -280;                                           1.00 a                                          
1dmc        1                                                                         1.00 a     Cd-6 Metallothionein-1                          
1dsb  A     2     1.22563    9 - 60;129 -187;                                         0.71 ab    Disulfide Bond Formation Protein
                          66 -127;                                                    1.00 a                                          
1dts        2     1.16583    2 -115;                                                  0.68 ab    Dethiobiotin Synthase                 
                         141 -203;                                                    0.58 ab                                         
1dyn  A     2m    1.12180   62 -119;                                                  0.41 ab    Dynamin Pleckstrin Homology domain        0.22 ab ,b
                          12 - 58;                                                    0.00 b                                          
1eca        2m    1.22439   20 - 71; 94 -111;                                         1.00 a     Hemoglobin                                1.00 a    
                           3 - 14; 77 - 87;118 -135;                                  1.00 a                                          
1ede        2     1.15688   23 - 80; 99 -163;231 -307;                                0.63 ab    Haloalkane Dehalogenase               
                           4 -  5; 90 - 91;172 -227;                                  0.90 a                                          
1eft        3     1.62789   11 - 36; 66 -209;                                         0.68 ab    Elongation Factor Tu                    
                         222 -305;                                                    0.00 b                                          
                         313 -403;                                                    0.00 b                                          
1enh        1                                                                         1.00 a     Engrailed Homeodomain                 
1epa  B     1                                                                         0.25 ab    Epididymal Retinoic Acid-binding Prote
1erb        1                                                                         0.18 b     Retinol Binding Protein                    
1erc        1                                                                         1.00 a     Pheromone Er-1                             
1erd  -     1                                                                         1.00 a     Pheromone Er-2                                  
1erg        2m    1.35378   25 - 64;                                                  0.00 b     Human Complement Regulatory Protein       0.00 b    
                           3 - 17;                                                    0.00 b                                          
1eri  A     2m    1.23561   21 -114;147 -170;221 -275;                                0.62 ab    Eco Ri Endonuclease                       0.60 ab   
                         118 -121;179 -191;                                           0.33 ab                                         
1erp        1                                                                         1.00 a     Pheromone Er-10                       
1etb  1     2m    1.29649   12 - 24; 54 - 55;104 -123;                                0.00 b     Transthyretin (Prealbumin)                0.11 b
                            29 - 48 ; 67 - 73 ; 91 - 97 ;                             0.19 b
1fba  A     3m    1.09702    9 - 32; 73 -107;130 -151;183 -190;227 -301;              0.57 ab    Fructose-1,6-bisphosphate Aldolase        0.74 ab 
                           36 - 63;307 -337;                                          1.00 a
                        112 -124;160 -179;198 -218;                                   0.87 a
1fc2  C     1                                                                         1.00 a     Immunoglobulin Fc                     
1fc2  D     2     1.60618  347 -441;                                                  0.09 b     Immunoglobulin Fc                     
                         240 -336;                                                    0.20 b                                          
1fcd  A     2     1.34815    4 - 40; 59 -108;256 -324;                                0.48 ab    Flavocytochrome C Sulfide Dehydrogenase
                          45 - 49;132 -252;333 -398;                                  0.53 ab                                         
1fcd  C     2     1.48010   87 -172;                                                  1.00 a     Flavocytochrome C Sulfide Dehydrogenase
                           4 - 74;                                                    1.00 a                                          
1fct  -     1                                                                         1.00 a     Immunoglobulin Fc 
1fha        2m    1.04246   14 -136;                                                  1.00 a     Ferritin                                  1.00 a    
                         138 -181;                                                    1.00 a                                          
1fia  B     1                                                                         1.00 a     Fis Protein                              
1fkb        1                                                                         0.16 b     Fk506 Binding Protein                              
1fnc        2     1.36457  164 -313;                                                  0.64 ab    Ferredoxin                            
                          38 -151;                                                    0.13 b                                          
1fod  4     1                                                                         1.00 a     Immunoglobulin Fc                              
1frp  A     2     1.34048   13 - 48; 74 -198;                                         0.44 ab    Fructose-1,6-bisphosphatase                              
                         209 -333;                                                    0.73 ab                                         
1fru  B     2m    1.31283   36 - 45; 78 - 94;                                         0.00 b     Fc (Igg) Receptor                         0.00 b    
                           6 - 30; 50 - 51; 62 - 70;                                  0.00 b                                          
1fxi  A     1                                                                         0.23 ab ,b Ferredoxin I                          
1fxr  A     2m    1.02287    3 -  6; 44 - 62;                                         0.56 ab    Ferredoxin I (4fe-4s)                     0.52 ab   
                          16 - 36;                                                    0.45 ab                                         
1gal        3     1.40309    4 - 63;133 -146;171 -173;228 -287;544 -581;              0.50 ab    Glucose Oxidase                       
                         116 -124;151 -156;185 -213;330 -427;458 -506;                0.69 ab                                         
                          80 - 94;294 -326;434 -451;512 -513;                         0.38 ab                                         
1gau  A     1                                                                         0.56 ab    Erythroid Transcription Factor           
1gca        2     1.52568  112 -255;296 -298;                                         0.71 ab    Glucose/Galactose-binding protein 
                           3 -109;258 -292;                                           0.66 ab                                         
1gdh  A     2     1.64753  102 -284;                                                  0.67 ab    D-glycerate Dehydrogenase             
                           4 - 95;293 -321;                                           0.66 ab                                         
1ghs  A     4m    1.46334    2 - 53; 85 - 93;123 -129;163 -166;227 -232;271 -273;     0.29 ab    1,3-beta-glucanase                          0.67 ab 
                           169 -202 ;244 -255 ;                                       0.86 a
                       133 -159 ;205 -220 ;                                           0.88 a
                        59 - 76 ;103 -117 ;                                           1.00 a
1gky        3     1.29146    4 - 31; 82 -121;164 -183;                                0.66 ab    Guanylate Kinase                      
                          34 - 81;                                                    0.32 ab                                         
                         125 -157;                                                    1.00 a                                          
1glc  G     3     1.14671    5 -244;438 -450;                                         0.57 ab    Glycerol Kinase                          
                         245 -306;405 -433;466 -470;                                  0.31 ab                                         
                         310 -399;479 -493;                                           0.90 a                                          
1gmf  A     2m    1.17423   33 - 64; 98 -116;                                         0.74 ab    Granulocyte-macrophage Colony-stimulat     0.85 a    
                          13 - 28; 74 - 87;                                           1.00 a                                          
1gof        3     1.30035  160 -529;578 -580;                                         0.03 b     Galactose Oxidase                     
                         546 -575;588 -638;                                           0.00 b                                          
                           7 -147;                                                    0.00 b                                          
1gox        2     1.08021   33 -155;213 -356;                                         0.71 ab    Glycolate Oxidase                     
                           8 - 26;165 -205;                                           1.00 a                                          
1gp1  A     1                                                                         0.57 ab    Glutathione Peroxidase                
1gph  1     2     1.40801  235 -442;                                                  0.70 ab                                          
                           2 -226;                                                    0.39 ab                                         
1gpr        2     1.08835   51 -115;                                                  0.00 b     Glucose Permease                      
                          21 - 47;129 -161;                                           0.13 b                                          
1gpt        1                                                                         0.39 ab    Gamma-1-h Thionin                          
1gtr  A     5c    2.05790  341 -342;465-543;                                          0.00 b     Glutaminyl-trna Synthetase              
                           344 -460;                                                  0.79 a,ab 
                          10 - 98;211 -278;303 -313;                                  0.67 ab 
                         103 -209;                                                    0.00 b
                          (293 -299;324-338;)
1har        2     1.71241   28 - 83;130 -146;                                         0.56 ab    Hiv-1 Reverse Transcriptase              
                         105 -110;156 -211;                                           0.68 ab                                         
1hcd        4m    1.16850   75 -104;                                                  0.00 b     Hisactophilin                             0.00 b    
                           5 - 24;114 -116;                                           0.00 b                                          
                          52 - 64;                                                    0.00 b                                          
                          35 - 46;                                                    0.00 b                                          
1hcg  B     2m    1.89298   27 - 38;                                                  0.00 b     Blood Coagulation Factor Xa               0.00 b    
                          11 - 22;                                                    0.00 b                                          
1hcn  A     2m    2.04699   11 - 29; 59 - 85;                                         0.00 b     Human Chorionic Gonadotropin              0.10 b    
                          35 - 56;                                                    0.33 ab                                         
1hcn  B     1                                                                         0.00 b     Human Chorionic Gonadotropin          
1hcr  A     1                                                                         1.00 a     Hin Recombinase                       
1hdc  A     3m    1.18952    8 - 58; 83 - 86;132 -137;175 -182;214 -239;              0.46 ab    3-alpha, 20-beta-hydroxysteroid Dehydr    0.68 ab   
                         101 -111;188 -193;                                           1.00 a                                          
                          64 - 78;113 -129;                                           1.00 a                                          
1hdg  O     2     1.47010    2 -145;315 -327;                                         0.55 ab    Holo-d-glyceraldehyde-3-phosphate Dehy
                         149 -311;                                                    0.43 ab                                         
1hex        4c    1.42190   99 -133;159 -249;                                         0.64 ab    3-isopropylmalate Dehydrogenase         
                           2 - 96;258 -300;                                           0.67 ab                                         
                         305 -344;                                                    1.00 a                                          
                        (145 -152;)
1hfc        1                                                                         0.63 ab    Fibroblast Collagenase                
1hfi        1                                                                         0.00 b     Factor H, 15th C-module Pair            
1hgj  A     2     1.65626   66 - 71;100 -259;                                         0.25 ab    Hemagglutinin                                
                          24 - 60; 86 - 89;266 -317;                                  0.00 b                                           
1hjr  A     2m    1.14489    2 - 34; 60 - 67; 98 -151;                                0.44 ab    Holliday Junction Resolvase               0.62 ab 
                        40 - 58; 77 - 92;                                             1.00 a
1hks        1                                                                         0.76 a,ab  Heat Shock Transcription Factor       
1hlb        3m    1.30202   34 - 64;111 -129;                                         1.00 a     Hemoglobin                                1.00 a 
                        68 -106 ;                                                     1.00 a
                        14 - 30 ;136 -150 ;                                           1.00 a
1hle  A     2     1.30440   24 -193;291 -357;                                         0.58 ab    Horse Leukocyte Elastase Inhibitor            
                         204 -289;                                                    0.21 ab ,b                                      
1hle  B     1                                                                         0.00 b     Horse Leukocyte Elastase Inhibitor            
1hmy        2     1.53590   13 -172;308 -323;                                         0.58 ab    Hhai Dna (Cytosine-c5-)-methyltransfer
                         192 -302;                                                    0.58 ab                                         
1hne  E     2     1.33087   30 -108;235 -242;                                         0.18 b     Human Neutrophil Elastase             
                          20 - 21;135 -230;                                           0.00 b                                          
1hng  A     2     1.99552    3 - 98;                                                  0.00 b     Cd2 (Rat)                             
                         105 -170;                                                    0.00 b                                          
1hoe        1                                                                         0.00 b     Alpha-Amylase Inhibitor Hoe-467A      
1hre        1                                                                         0.00 b     Heregulin-alpha                                
1hrt  I     1                                                                         0.00 b     Alpha-thrombin                        
1hsl  A     2     1.28655    7 - 89;194 -228;                                         0.69 ab    Histidine-binding Protein                      
                          92 -181;                                                    0.50 ab                                         
1htm  B     1                                                                         0.96 a     Hemagglutinin Ectodomain                      
1htp        2     1.33308    8 - 27; 49 - 50; 74 - 79;101 -105;                       0.00 b     H-protein                                
                          29 - 42; 55 - 69; 82 - 92;                                  0.47 ab                                         
1htr  P     1                                                                         1.00 a     Progastricsin                          
1huc  B     2     1.18125   56 -167;247 -248;                                         0.88 a     Cathepsin B                           
                         170 -234;                                                    0.00 b                                          
1hun  A     1                                                                         0.48 ab    Human Macrophage Inflammatory Protein 
1huw        1                                                                         1.00 a     Human Growth Hormone                     
1hvd        4     1.63625   88 -157;191 -200;232 -245;                                1.00 a     Annexin V                                
                          17 - 85;306 -315;                                           1.00 a                                          
                         247 -303;                                                    1.00 a                                          
                         169 -184;203 -225;                                           1.00 a                                          
1iae        3c    1.55953   14 - 98;                                                  0.54 ab    Astacin                                          
                            (2 - 3;134 - 135;184 - 198;)
                            (113 - 115; 164 - 166;)
1iag        2     1.25802    6 -147;                                                  0.62 ab    Adamalysin II                         
                         158 -193;                                                    0.67 ab                                         
1ifc        1                                                                         0.17 b     Intestinal Fatty Acid Binding Protein 
1igp        1                                                                         0.34 ab    Inorganic Pyrophosphatase             
1ilr  1     2m    1.01122   22 - 33; 65 - 81;120 -143;                                0.00 b                                               0.00 b    
                          11 - 17; 46 - 60; 99 -113;146 -150;                         0.00 b                                          
1irk        3     1.59870  1084 -1148;1188 -1204;1236 -1274;                          0.92 a     Insulin Receptor 
                         996 -1077;                                                   0.25 ab                                           
                         1163 -1183;1215 -1223;                                       0.79 a,ab                                       
1isc  A     3m    1.37555   87 -113;130 -153;178 -186;                                0.71 ab    Iron(Iii) Superoxide Dismutase            0.81 a    
                          20 - 26;118 -124;159 -173;                                  0.73 ab                                         
                          29 - 75;                                                    1.00 a                                          
1isu  A     1                                                                         0.60 ab    High-potential Iron-sulfur Protein 
1ivd        2     1.06443  121 -313;407 -413;                                         0.00 b     Influenza A Subtype N2 Neuraminidase 
                          96 -102;353 -392;418 -449;                                  0.00 b                                          
1kab        2m    1.10411   10 - 36; 72 - 94;                                         0.00 b     Staphylococcal Nuclease                   0.33 ab   
                          39 - 40; 97 -134;                                           0.77 a,ab                                       
1knb        1                                                                         0.00 b     Adenovirus Type 5 Fiber Protein (Recep
1knt        1                                                                         0.36 ab    Collagen Type Vi (Kunitz-type Domain C
1ktx        1                                                                         0.00 b     Kaliotoxin (Ktx) (Nmr, 11 Structures)
1lba        1                                                                         0.61 ab    Lysozyme Mutant With Ala 6 Replaced By
1ldm        2     1.37456   22 -160;247 -325;                                         0.65 ab    M=4= Lactate Dehydrogenase Ternary Com
                         164 -242;                                                    0.90 a                                          
1len  A     3m    1.59446   82 -151;                                                  0.00 b     Lentil lectin                             0.00 b    
                          18 - 46;                                                    0.00 b                                          
                          63 - 70;159 -178;                                           0.00 b                                          
1lga  A     2     1.26361   54 - 57;151 -273;                                         0.88 a     Lignin Peroxidase      
                          16 - 49; 70 -130;283 -284;                                  0.94 a                                          
1lis        1                                                                         1.00 a     Lysin                                 
1lki        2m    1.24684   10 - 11; 76 -142;                                         0.93 a     Leukemia Inhibitory Factor                0.96 a    
                          22 - 59;155 -177;                                           1.00 a                                          
1loe  B     1                                                                                    Legume lectin  
1lpb  A     2m    1.89698   48 - 50; 67 - 70; 84 - 89;                                0.00 b     Lipase                                    0.00 b    
                          28 - 39; 57 - 58;                                           0.00 b                                          
1lpb  B     2     1.41935    2 -327;                                                  0.64 ab    Lipase
                         338 -448;                                                    0.00 b                                          
1lpe        1                                                                         1.00 a     Apolipoprotein-E3 
1lts  A     2m    1.25757    5 - 22; 66 - 88;119 -141;                                0.39 ab    Heat-labile Enterotoxin (Lt)              0.45 ab   
                          41 - 63; 94 -116;158 -161;                                  0.54 ab                                         
1lts  C     1                                                                         1.00 a     Heat-labile Enterotoxin (Lt)                         
1lts  D     2     1.20510   26 - 77;                                                  0.55 ab    Heat-labile Enterotoxin (Lt)          
                           5 - 22; 82 -100;                                           0.21 ab ,b                                      
1lyp        1                                                                         1.00 a     Cap18 (Residues 106 - 137)
1mat        3     1.19648   70 - 78;120 -164;206 -233;                                0.61 ab    Methionine Aminopeptidase             
                         170 -203;236 -261;                                           0.00 b                                          
                           8 - 57; 93 -114;                                           0.61 ab                                         
1mdc        1                                                                         0.16 b     Fatty Acid Binding Protein
1min  A     3     1.58489    6 - 34;350 -467;                                         0.75 a,ab  Nitrogenase Molybdenum-iron Protein   
                          63 -205;                                                    0.79 a,ab                                       
                         222 -346;                                                    0.77 a,ab                                       
1mmo  B     1                                                                         1.00 a     Methane Monooxygenase Hydrolase       
1mmo  G     2m    1.39509   10 - 79;                                                  1.00 a     Methane Monooxygenase Hydrolase           1.00 a    
                          87 -143;                                                    1.00 a                                          
1mrg        2     1.30245    2 - 24; 47 -172;                                         0.68 ab    Alpha-momorcharin
                          27 - 37;183 -235;                                           0.53 ab                                         
1mrt        1                                                                                    Cd-7 Metallothionein-2
1msf  C     2     1.64219  152 -185;                                                  1.00 a     C-myb Dnab inding Domain
                         100 -133;                                                    1.00 a                                          
1mup        2m    1.07213   25 - 36; 84 -154;                                         0.28 ab    Major Urinary Protein                     0.18 b    
                          21 - 22; 45 - 77;                                           0.00 b                                          
1myl  B     1                                                                         1.00 a     Arc Repressor   
                          21 - 22; 45 - 77;                                           0.00 b                                          
1myp  C     4     1.64602  304 -331;435 -508;                                         1.00 a     Myeloperoxidase                       
                         342 -381;533 -562;                                           0.62 ab                                         
                         174 -293;522 -528;                                           1.00 a                                          
                         128 -144;417 -428;                                           0.75 a                                          
1nar        2m    1.08866    4 - 56; 79 -115;126 -288;                                0.60 ab    Narbonin                                  0.62 ab   
                          60 - 74;117 -122;                                           0.78 a,ab                                       
1nba  A     2m    1.11546   45 - 50; 68 - 84;166 -233;                                0.69 ab    N-carbamoylsarcosine Amidohydrolase       0.62 ab   
                          54 - 57; 89 -144;                                           0.27 ab                                         
1nhk  L     2c    1.11837    3 - 40; 72 -132;                                         0.59 ab    Nucleoside Diphosphate Kinase
                            (44 - 67;)                   
1nip  B     2m    1.07038    3 -211;235 -249;                                         0.73 ab    Nitrogenase Iron Protein                  0.75 ab   
                         216 -230;                                                    1.00 a                                          
1oct  C     2     1.76768    6 - 74;                                                  1.00 a     Oct-1 (Pou Domain)                    
                         110 -159;                                                    1.00 a                                          
1ofv        2m+   1.05570    3 - 53; 82 -166;                                         0.55 ab    Flavodoxin                                0.55 ab   
                          56 - 69;                                                    0.60 ab                                         
1olb  A     3     1.50353   48 -175;424 -475;                                         0.67 ab    Oligo-peptide Binding Protein
                         264 -417;479 -490;                                           0.54 ab                                         
                          14 - 43;191 -259;495 -514;                                  0.49 ab                                         
1oma        1                                                                         0.00 b     Omega-aga-IVB    
1omp        2     1.27473    7 -111;167 -182;258 -329;                                0.62 ab    D-maltodextrin-binding Protein        
                         114 -163;186 -245;336 -368;                                  0.81 a                                          
1ovb        1                                                                         0.52 ab    Ovotransferrin
1oxy        4     1.46657  383 -399;442 -465;484 -503;552 -566;617 -627;              0.11 b     Hemocyanin Subunit II
                           3 -126;241 -248;517 -520;                                  0.94 a                                          
                         161 -217;405 -438;510 -511;538 -539;580 -583;                0.63 ab                                         
                         266 -375;                                                    0.91 a                                          
1oyb        2m    1.16912   20 -116;163 -191;217 -393;                                0.71 ab    Old Yellow Enzyme                         0.72 ab   
                         124 -160;197 -202;                                           0.79 a,ab                                       
1paa        1                                                                         1.00 a     Yeast Transcription Factor Adr1
1pbe        2     1.34712   47 - 99;175 -274;328 -386;                                0.54 ab    P-hydroxybenzoate Hydroxylase  
                           5 - 40;102 -167;277 -318;                                  0.59 ab                                         
1pbp        2     1.04766   69 -228;285 -295; Title                                   0.62 ab                                          
                           3 - 67;253 -283;298 -314;                                  0.68 ab                                         
1pcr  H     1                                                                         0.45 ab    Photosynthetic Reaction Center        
1pcr  L     4m    1.52261  116 -162;225 -250;                                         1.00 a     Photosynthetic Reaction Center            0.96 a    
                          24 -111;                                                    0.90 a                                          
                         259 -273;                                                    1.00 a                                          
                         171 -220;                                                    1.00 a                                          
1pda        3     1.635  5 - 98;201 -216;                                             0.55 ab    Phorphobilinogen deaminase
                           106- 186;                                                  0.60 ab     
                           222- 304;                                                  0.59 ab 
1pdc        1                                                                         0.00 b     Seminal Fluid Protein Pdc-109
1pdg  B     3m    1.76428   17 - 62; 97 - 99;                                         0.00 b     Platelet-derived Growth Factor            0.00 b    
                          65 - 74; 85 - 94;                                           0.00 b                                          
                          77 - 82;                                                    0.00 b                                          
1pet  A     1                                                                         1.00 a     Tumor Antigen P53
1pfi  A     1                                                                         1.00 a     Major Coat Protein Of Pf1 Virus
1pfk  A     2     1.66217    3 -123;258 -302;                                         0.65 ab    Phosphofructokinase 
                         139 -246;309 -318;                                           0.77 a,ab                                       
1pgb        1                                                                         0.37 ab    Protein G (B1 Igg-binding Domain)     
1pho        1                                                                         0.02 b     Phosphoporin                   
1php        3     1.49183   15 -167;386 -389;                                         0.66 ab    3-phosphoglycerate Kinase (Pgk)       
                         169 -217;243 -261;297 -380;                                  0.78 a,ab                                       
                         221 -228;265 -295;                                           0.35 ab                                         
1pii        2     1.42828    4 -211;229 -237;                                         0.65 ab    N-(5'phosphoribosyl)anthranilate Isomerase
                         217 -223;242 -445;                                           0.64 ab                                         
1pk4        2m    2.13793    1 -  2; 78 - 79;                                         0.00 b     Plasminogen Kringle 4                     0.00 b    
                          62 - 74;                                                    0.00 b                                          
1pkn        3     1.51134   45 -112;222 -387;                                         0.74 ab    Pyruvate Kinase
                          17 - 30;390 -528;                                           0.76 a,ab                                       
                         138 -209;                                                    0.00 b                                          
1plq        2     1.38791  135 -250;                                                  0.25 ab    Proliferating Cell Nuclear Antigen
                           2 -117;                                                    0.25 ab ,b                                      
1pmy        2m    1.11493    2 - 92;                                                  0.00 b     Pseudoazurin (Cupredoxin)                 0.28 ab   
                          99 -120;                                                    1.00 a                                          
1pnt        1                                                                         0.74 ab    Tyrosine Phosphatase 
1poa        1                                                                         0.86 a     Phospholipase A2                      
1poc        2     1.23579   40 - 59; 95 -129;                                         0.00 b     Phospholipase A2     
                          25 - 35; 61 - 89;                                           1.00 a                                          
1pox  A     2     1.28202   10 -178;373 -543;                                         0.67 ab    Pyruvate Oxidase  
                         199 -364;564 -588;                                           0.78 a,ab                                       
1ppb  L     1                                                                         1.00 a     Alpha-thrombin           
1ppn        1                                                                         0.56 ab    Papain        
1ppt  -     1                                                                         1.00 a     Avian Pancreatic Polypeptide
1prc  C     4     1.60197  102 -136;262 -309;                                         1.00 a     Photosynthetic Reaction Center        
                           8 - 34;244 -247;                                           0.78 a,ab                                       
                         172 -239;                                                    1.00 a                                          
                          52 - 81;                                                    1.00 a                                          
1prs        2+    1.37928    4 - 86;119 -122;                                         0.26 ab    Development-specific Protein S 
                          93 -113;131 -173;                                           0.00 b                                          
1prt  A     2     1.00697    6 - 11; 23 - 54; 97 -136;191 -227;                       0.52 ab    Pertussis Toxin                       
                          15 - 21; 57 - 92;141 -162;                                  0.51 ab                                         
1prt  B     2     1.50457   27 - 92;                                                  0.39 ab    Pertussis Toxin                       
                         100 -190;                                                    0.23 ab ,b                                      
1prt  D     1                                                                         0.16 b     Pertussis Toxin                       
1prt  F     1                                                                         0.26 ab    Pertussis Toxin                       
1psm        1                                                                         1.00 a     Spam-h1
1psp  A     2m    2.14904    6 - 47;                                                  0.71 ab    Pancreatic Spasmolytic Polypeptide        0.67 ab   
                          75 - 96;                                                    0.60 ab                                         
1ptx        1                                                                         0.32 ab    Scorpion Toxin Ii                     
1pxt  B     3c    1.07878   36 - 72; 88 -158;228 -287;                                0.48 ab    Peroxisomal 3-ketoacyl-coa Thiolase   
                         202 -220;300 -415;                                           0.66 ab                                         
                        (76 -80;288 -294;)
1pya  B     3     1.22776  152 -202;236 -261;                                         0.00 b     Pyruvoyl-dependent Histidine Decarboxy
                          99 -102;124 -134;278 -297;                                  1.00 a                                          
                         108 -122;207 -231;                                           0.71 ab                                         
1pyp        2m    1.29328  120 -229;                                                  0.62 ab    Inorganic Pyrophosphatase                 0.53 ab   
                           4 - 19;                                                    0.00 b                                          
1rbl  M     1                                                                         0.52 ab    Ribulose 1,5 Bisphosphate CarboxylaseO
1rcb        1                                                                         0.93 a     Interleukin 4                         
1rec        2     1.31479  102 -194;                                                  0.93 a     Recoverin  
                          10 - 94;                                                    0.90 a                                          
1ret        1                                                                         1.00 a     Gamma Delta Resolvase 
1rfb  A     1                                                                         1.00 a     Interferon Gamma 
1rib  A     2     1.12735   34 -149;207 -253;269 -318;                                1.00 a     Protein R2 Of Ribonucleotide Reductase
                         153 -205;259 -267;                                           0.82 a                                          
1rmi        1                                                                         1.00 a     Interferon-beta
1rop  A     1                                                                         1.00 a     Rop
1rpa        2     1.24557    2 -141;220 -340;                                         0.70 ab    Prostatic Acid Phosphatase
                         143 -215;                                                    1.00 a                                          
1rsy        2     1.54351  179 -194;223 -246;                                         0.00 b     Synaptotagmin I
                         144 -166;205 -212;256 -261;                                  0.00 b                                          
1rtp  1     2m    1.15612   40 - 64; 79 -107;                                         0.90 a     Alpha-parvalbumin                         0.94 a    
                           2 - 32; 66 - 70;                                           1.00 a                                          
1rva  A     2m    1.11854    3 - 17; 37 -241;                                         0.55 ab    Eco Rv Endonuclease                       0.53 ab   
                          22 - 32;                                                    0.00 b                                          
1s01        1                                                                         0.64 ab    Subtilisin BPN'
1sac  A     1                                                                         0.08 b     Serum Amyloid P Component       
1sbp        2     1.28993   97 -217;279 -308;                                         0.72 ab    Sulfate-binding Protein               
                           2 - 94;222 -270;                                           0.72 ab                                         
1scm  A     1                                                                         1.00 a     Myosin
1scm  B     2     1.69265   88 -148;                                                  0.85 a     Myosin            
                          14 - 77;                                                    1.00 a                                          
1scm  C     2     1.72643   83 -149;                                                  0.83 a     Myosin            
                           8 - 76;                                                    0.90 a                                          
1scu  A     2     1.42113    9 -135;                                                  0.58 ab    Succinyl-coa Synthetase
                         144 -287;                                                    0.64 ab                                         
1scu  B     3     1.90334  240 -387;                                                  0.73 ab    Succinyl-coa Synthetase
                           5 - 15;104 -231;                                           0.56 ab                                         
                          22 -100;                                                    0.54 ab                                         
1scy        1                                                                         0.56 ab    Scyllatoxin (Leiurotoxin I)
1ses  A     3     1.28122    4 - 21;118 -123;186 -384;                                0.43 ab    Seryl-trna Synthetase
                         136 -182;386 -417;                                           0.92 a                                          
                          27 - 98;                                                    1.00 a                                          
1smr  A     3     1.38554  191 -306;                                                  0.30 ab    Renin
                          13 -142;                                                    0.15 b                                          
                           2 -  9;150 -183;309 -325;                                  0.00 b                                          
1spf        1                                                                         0.00 a     Pulmonary Surfactant-associated Polype
1srg  A     1                                                                         0.00 b     Streptavidin
1tab  I     1                                                                         0.00 b     Trypsin Complex With Bowman-Birk Inhib
1tad  A     2     1.36656   28 - 53;181 -341;                                         0.62 ab    Transducin-alpha
                          59 -172;                                                    1.00 a                                          
1tap        1                                                                         0.40 ab    Factor Xa Inhibitor
1tca        2     1.20842   13 -131;179 -287;                                         0.71 ab    Lipase (Triacylglycerol Hydrolase)    
                         142 -169;309 -314;                                           0.82 a                                          
1tfi        1                                                                         0.00 b     Transcriptional Elongation Factor Sii 
1tgs  I     1                                                                         0.50 ab    Trypsinogen
1thv        2m    1.19091    2 -126;180 -203;                                         0.00 b     Thaumatin Isoform A                       0.22 ab ,b
                         130 -176;                                                    1.00 a                                          
1tie        1                                                                         0.00 b     Erythrina Trypsin Inhibitor
1tlk        1                                                                         0.00 b     Telokin                               
1tml        2     1.22750   40 -256;                                                  0.74 ab    Endo-1,4-beta-d-glucanase             
                          12 - 32;276 -284;                                           1.00 a                                          
1tnr  A     1                                                                         0.00 b     Tumor Necrosis Factor Receptor P55
1tnr  R     3     2.37854   19 - 72;                                                  0.00 b     Tumor Necrosis Factor Receptor P55 
                         123 -152;                                                    0.00 b                                          
                          83 -116;                                                    0.00 b                                          
1tph  1     2m    1.09175    6 -127;160 -164;206 -244;                                0.59 ab                                              0.70 ab   
                         139 -151;178 -203;                                           1.00 a                                          
1tpl  A     4+    1.58872   21 - 46;312 -455;                                         0.75 a,ab  Tyrosine Phenol-lyase                 
                          92 -214;250 -286;                                           0.60 ab                                         
                          58 - 88;296 -308;                                           1.00 a                                          
                         218 -246;                                                    1.00 a                                          
1tpn        2m    1.42838   20 - 45;                                                  0.00 b     Tissue-type Plasminogen Activator         0.00 b    
                           6 - 15;                                                    0.00 b                                          
1trb        2     1.55792    3 -116;245 -313;                                         0.48 ab    Thioredoxin Reductase 
                         122 -241;                                                    0.45 ab                                         
1trk  A     4     1.62656    6 -300;                                                  0.80 a     Transketolase                         
                         356 -542;591 -596;                                           0.70 ab                                         
                         547 -587;599 -667;                                           0.67 ab                                         
                         302 -335;                                                    1.00 a                                          
1trz  B     1                                                                         1.00 a     Insulin (T3r3)
1tss  A     2     1.31020   18 - 98;119 -124;181 -182;                                0.00 b     Toxic Shock Syndrome Toxin 1          
                           4 - 14;102 -110;126 -167;186 -194;                         0.47 ab                                         
1tvs        1                                                                         1.00 a     Transactivator Protein
1tys        1                                                                         0.53 ab    Thymidylate Synthase
1ula        2     1.22058  116 -218;234 -278;                                         0.55 ab    Purine Nucleoside Phosphorylase       
                           8 -113;222 -230;                                           0.60 ab                                         
1vaa  A     2     1.49617    3 -179;                                                  0.55 ab    Mhc Class I H-2k==b==
                         186 -272;                                                    0.00 b                                          
1vil        2m    1.10373   46 -109;                                                  0.59 ab    Villin                                    0.45 ab   
                          20 - 40;115 -117;                                           0.00 b                                          
1vmo  A     1                                                                         0.00 b     Vitelline Membrane Outer Layer Protein
1was        1                                                                         1.00 a     Bacterial Aspartate Receptor
1wsy  A     2m    1.08418    2 - 24; 48 - 51; 78 -233;                                0.69 ab    Tryptophan Synthase                       0.79 a,ab 
                          30 - 42; 63 - 73;236 -264;                                  1.00 a                                          
1wsy  B     2     1.27986   59 - 77;207 -390;                                         0.59 ab    Tryptophan Synthase                   
                            22 - 51; 88 -203;                                         0.82 a                                          
1xnb        1                                                                         0.08 b     Xylanase (Endo-1,4-beta-xylanase)     
1ypt  A     1                                                                         0.63 ab    Protein-tyrosine Phosphatase
1ytb  A     2     1.37170   66 -165;                                                  0.37 ab    Tatab ox Binding Protein
                         172 -236;                                                    0.59 ab                                         
1zaa  C     2     1.41278   35 - 82;                                                  0.71 ab    Zif268 Immediate Early Gene 
                           5 - 30;                                                    0.75 ab                                         
2abk        3     1.43547    3 - 16;139 -185;                                         1.00 a
                          29 - 54;108 -130;                                           1.00 a
                          61 - 98;                                                    1.00 a
2ach  B     1                                                                         0.00 b     Alpha1 Antichymotrypsin
2ak3  A     2c    1.17790    7 -113;164 -211;                                         0.79 a,ab  Adenylate Kinase Isoenzyme-3     
                          (116 -137;)  
2alp        2     1.07851   15B-120K;231 -242;                                        0.13 b     Alpha-lytic Protease                  
                         135 -230;                                                    0.00 b                                          
2atc  B     1                                                                         0.60 ab    Aspartate Carbamoyltransferase
2ayh        1                                                                         0.04 b     1,3-1,4-beta-d-glucan 4 Glucanohydrola
2aza  A     1                                                                         0.26 ab    Azurin                      
2bbk  H     3     1.41682   69 -203;                                                  0.00 b     Methylamine Dehydrogenase      
                         219 -320;                                                    0.09 b                                          
                          33 - 64;322 -368;                                           0.00 b                                          
2bbv  A     2m    1.08002   91 -323;                                                  0.08 b     Black Beetle Virus Capsid Protein         0.22 ab ,b
                          61 - 71;334 -352;                                           0.92 a                                          
2bds        1                                                                         0.00 b     BDS-I
2bop  A     1                                                                         0.44 ab    Bovine Papillomavirus-1 E2 
2bpa  1     2     1.32643   10 -161;235 -290;402 -423;                                0.28 ab                                          
                         192 -221;301 -383;                                           0.84 a                                          
2bpa  2     1                                                                         0.00 b     Bacteriophage Phix174 Capsid Proteins 
2bpa  3     1                                                                                    Bacteriophage Phix174 Capsid Proteins
2btf  P     1                                                                         0.45 ab    Beta-actin-profilin Complex
2cas        2c    1.06691   49 -399;455 -580;                                         0.13 b     Canine Parvovirus Empty Capsid
                           (415-430;)
2cba        1                                                                         0.18 b     Carbonic Anhydrase II    
2cbh        1                                                                         0.00 b     C-terminal Domain Of Cellobiohydrolase
2ccy  A     1                                                                         1.00 a     Cytochrome c'                   
2cdv        2m    1.31200    9 - 20; 65 - 98;                                         0.79 a,ab  Cytochrome c=3=                           0.73 ab   
                          30 - 41;                                                    0.50 ab                                         
2chs  A     2m    1.08196    3 - 11; 42 - 49; 73 -108;                                0.00 b     Chorismate Mutase                         0.42 ab   
                          17 - 35; 60 - 64;                                           1.00 a                                          
2cnd        2     1.29636  119 -269;                                                  0.52 ab    Nadh-dependent Nitrate Reductase
                          13 -116;                                                    0.14 b                                          
2cp4        4     1.54823   53 - 95;298 -327;                                         0.45 ab    Cytochrome P450cam
                          38 - 42;147 -153;174 -185;235 -264;382 -405;                0.81 a                                          
                         121 -142;157 -167;268 -291;360 -377;                         1.00 a                                          
                         108 -119;193 -232;                                           0.91 a                                          
2cpl        1                                                                         0.29 ab    Cyclophilin A                         
2crd        1                                                                         0.62 ab    Charybdotoxin    
2cro        1                                                                         1.00 a     434 Cro Protein                       
2ctc        1                                                                         0.70 ab    Carboxypeptidase A
2cts        4     1.44416   57 -116;209 -234;328 -340;375 -384;                       0.93 a     Citrate Synthase - (CoA, Citrate)
                         122 -194;243 -269;393 -414;                                  1.00 a                                          
                         277 -310;345 -363;                                           1.00 a                                          
                          38 - 42;427 -434;                                           1.00 a
2dnj  A     2     1.19628    2 - 11; 34 - 40; 64 -232;255 -258;                       0.30 ab    Deoxyribonuclease I
                          13 - 30; 46 - 55;235 -249;                                  1.00 a                                          
2dri        2     1.48774  105 -234;266 -268;                                         0.70 ab    D-ribose-binding Protein
                           3 -103;237 -263;                                           0.63 ab                                         
2drp  A     2m    1.95667  104 -133;                                                  0.55 ab    Tramtrack Protein                         0.63 ab   
                         141 -163;                                                    0.73 ab                                         
2ebn        2+    1.16361   11 - 17; 41 -223;245 -249;                                0.46 ab    Endo-beta-n-acetylglucosaminidase F1  
                          29 - 31;232 -241;262 -280;                                  0.79 a,ab                                       
2ech        1                                                                         0.00 b     Echistatin 
2end        1                                                                         1.00 a     Endonuclease V                        
2gda        1                                                                         0.83 a     Glucocorticoid Receptor
2gdm        2m    1.15486   22 - 36;107 -122;                                         1.00 a     Leghemoglobin (Oxy)                       1.00 a
                           5 - 19; 58 - 81;                                           1.00 a
2glt        3     1.70479    3 -121;301 -313;
      0.52 ab 
                         208 -294;
      0.41 ab 
                         138 -199;
      0.53 ab 
2gst  A     2     1.33638    2 - 82;191 -197;                                         0.61 ab    Glutathione S-transferase
                          90 -114;130 -188;                                           1.00 a                                          
2hbg        2     1.13809   24 - 71;103 -118;                                         1.00 a     Hemoglobin                    
                           4 - 18; 76 - 89;124 -145;                                  1.00 a                                          
2hhm  A     2     1.10547    6 -141;190 -259;                                         0.57 ab    Human Inositol Monophosphatase Dimer C
                         154 -185;                                                    0.70 ab                                         
2hip  A     1                                                                         0.00 b     High Potential Iron Sulfur Protein
2hmz  A     1                                                                         1.00 a     Hemerythrin                
2hnq        2+    1.26129   69 -214;                                                  0.29 ab    Protein-tyrosine Phosphatase 1b
                           6 - 26;220 -278;                                           1.00 a                                          
2hnt  E     1                                                                         0.50 ab    Gamma-thrombin                        
2hpd  A     4     1.40306  112 -158;251 -324;403 -450;                                0.87 a     Cytochrome P450 (Bm-3) 
                          25 - 69;330 -367;                                           0.46 ab                                         
                          94 -103;198 -238;                                           1.00 a                                          
                          73 - 82;172 -189;                                           1.00 a                                          
2hpe  A     1                                                                         0.13 b     Hiv-2 Protease
2hsp        2m    1.76276   41 - 55;                                                  0.00 b     Phospholipase C-gamma (Sh3 Domain)        0.00 b    
                           9 - 31;                                                    0.00 b                                          
2ihl        2     1.27144   43 - 98;                                                  0.56 ab    Lysozyme             
                           5 - 36;109 -114;                                           1.00 a                                          
2lgs  A     3c    1.29888  104 -135;189 -455;                                         0.70 ab    Glutamine Synthetase
                           2 - 92;                                                    0.31 ab                                         
                          (137 - 152;459 - 465;)
2liv        2     1.56353    3 -116;259 -316;                                         0.72 ab    Leu/Ile/Val-binding protein
                         124 -248;330 -342;                                           0.62 ab                                         
2mad  L     2c    1.41227   32 - 52; 76 -122;                                         0.00 b     Methylamine Dehydrogenase      
                            (57 - 74;126 -129;)          
2mev  1     1                                                                         0.14 b     Mengo Encephalomyocarditis Virus Coat
2mge        2m    1.06857    4 - 77;101 -118;                                         1.00 a     Myoglobin                                 1.00 a    
                          83 - 95;125 -149;                                           1.00 a                                          
2mnr        2     1.19044   22 - 29;123 -338;                                         0.69 ab    Mandelate Racemase                    
                           6 - 16; 32 -118;351 -357;                                  0.66 ab                                         
2mrb        1                                                                                    Cd-7 Metallothionein-2a 
2ms2  A     2m    1.18327    7 - 93;                                                  0.00 b     Ms2 Virus (Bacteriophage)                 0.26 ab   
                          98 -123;                                                    1.00 a                                          
2msb  A     2     1.15422  112 -152;214 -220;                                         0.54 ab    Mannose-binding Protein A
                         156 -208;                                                    0.00 b                                          
2mta  C     1                                                                         1.00 a     Methylamine Dehydrogenase
2ohx  A     3     1.59449  175 -316;                                                  0.67 ab    Alcohol Dehydrogenase
                          35 - 91;149 -169;324 -373;                                  0.44 ab                                         
                           7 - 28;130 -137;                                           0.00 b                                          
2pcd  A     2     1.19707   17 -109;126 -145;171 -188;                                0.15 b     Protocatechuate 3,4-dioxygenase       
                         114 -122;149 -167;                                           0.69 ab                                         
2pde        1                                                                         1.00 a     Dihydrolipoamide Acetyltransferase
2pgd        3     1.56958    5 -175;                                                  0.68 ab    6-phosphogluconate Dehydrogenase
                         178 -291;315 -348;392 -433;                                  1.00 a                                          
                         354 -381;                                                    1.00 a                                          
2phy        1                                                                         0.46 ab    Photoactive Yellow Protein
2pia        3     1.91805  113 -223;                                                  0.53 ab    Phthalate Dioxygenase Reductase
                         238 -319;                                                    0.21 ab ,b                                      
                           9 - 98;                                                    0.15 b                                          
2pmg  A     4     1.67964    4 -188;                                                  0.52 ab    Phosphoglucomutase                    
                         305 -382;408 -419;540 -549;                                  0.66 ab                                         
                         192 -303;390 -403;                                           0.76 a,ab                                       
                         421 -537;                                                    0.34 ab                                         
2por        1                                                                         0.09 b     Porin                
2reb        3     1.59416   39 - 40; 56 - 94;115 -144;166 -218;                       0.66 ab    Rec A Protein                         
                         270 -327;                                                    0.76 a,ab                                       
                          45 - 50;101 -106;221 -268;                                  0.25 a,ab                                       
2rn2        1                                                                         0.55 ab    Ribonuclease H                        
2rsl  B     1                                                                         0.69 ab    Gamma Delta Resolvase
2rsp  B     1                                                                         0.15 b     Rous Sarcoma Virus Protease  
2sas        2m    1.14916    4 -114;158 -170;                                         0.96 a     Sarcoplasmic Calcium-binding Protein      0.96 a    
                         124 -149;                                                    1.00 a                                          
2scp  A     2     1.19726   25 - 59; 90 -159;                                         0.95 a     Sarcoplasmic Calcium-binding Protein  
                           2 - 23; 70 - 82;                                           0.86 a                                          
2sil        1                                                                         0.07 b     Sialidase (Neuraminidase)             
2sn3        1                                                                         0.40 ab    Scorpion Neurotoxin       
2snv        2     1.31782  188 -263;                                                  0.00 b     Sindbis Virus Capsid Protein
                         115 -168;                                                    0.00 b                                          
2stv        2m    1.35497   43 - 46; 83 -135;170 -177;                                0.21 ab ,b Satellite Tobacco Necrosis Virus          0.10 b    
                          26 - 37; 64 - 77;142 -150;183 -193;                         0.00 b                                          
2tbv  A     2     1.49997  274 -376;                                                  0.00 b     Tomato Bushy Stunt Virus              
                         106 -264;                                                    0.07 b                                          
2tgi        2     1.49854   21 - 40; 83 -106;                                         0.14 b     Transforming Growth Factor-beta
                           4 - 18; 43 - 80;109 -112;                                  0.53 ab                                         
2tmd  A     3     1.72570   13 -336;                                                  0.66 ab    Trimethylamine Dehydrogenase          
                         350 -357;428 -431;489 -646;                                  0.48 ab                                         
                         391 -418;442 -485;649 -693;                                  0.73 ab                                         
2tmv  P     2c    1.35202   20 - 50; 76 -134;                                         0.63 ab    Intact Tobacco Mosaic Virus
                            (10 - 18; 68 - 70;138 -148;)
2tpr  A     3     1.62000   50 -114;161 -288;                                         0.66 ab    Trypanothione Reductase               
                         362 -477;                                                    0.47 ab                                         
                           2 - 34;119 -157;321 -348;                                  0.37 ab                                         
2ts1        2     1.24196    2 -220;                                                  0.77 a,ab  Tyrosyl-transfer RNA Synthetase       
                         248 -318;                                                    1.00 a                                          
2zta  A     1                                                                         1.00 a     GCN4 Leucine Zipper
3aah  A     7     1.98217   26 - 27;392 -405;444 -502;                                0.00 b     Methanol Dehydrogenase         
                           2 -  9;112 -193;                                           0.17 b                                          
                         305 -363;                                                    0.00 b                                          
                         375 -378;407 -433;534 -552;                                  0.33 ab                                         
                          41 - 47;512 -526;565 -570;                                  0.00 b                                          
                         241 -289;                                                    0.00 b                                          
                          59 - 90;                                                    0.00 b                                          
3aah  B     1                                                                         1.00 a     Methanol Dehydrogenase
3bcl        2     1.18536    4 - 68;122 -127;244 -279;300 -357;                       0.15 b     Bacteriochlorophyll-a Protein         
                          71 -117;136 -229;284 -290;                                  0.35 ab                                         
3cd4        2     1.28261  108 -177; Cd4                                              0.00 b     (N-terminal Fragment Consisting Of    
                           2 -102;                                                    0.00 b                                          
3chy        1                                                                         0.73 ab    CheY                                  
3cla        2     1.23874   32 - 67; 90 -214;                                         0.51 ab    Type III Chloramphenicol Acetyltransfe
                           8 - 27; 75 - 86;                                           0.43 ab                                         
3cox        4     1.64646   11 - 40;232 -287;470 -472;                                0.28 ab    Cholesterol Oxidase                   
                         162 -204;324 -380;407 -424;                                  0.62 ab                                         
                          96 -109;290 -303;388 -399;444 -445;                         0.41 ab                                         
                         128 -155;487 -504;                                           1.00 a                                          
3dfr        2+    1.24410   38 -105;                                                  0.58 ab    Dihydrofolate Reductase
                           2 - 32;112 -160;                                           0.20 ab ,b                                      
3ebx        2m    1.15942   23 - 49;                                                  0.00 b     Erabutoxin b                              0.00 b    
                           2 - 15;                                                    0.00 b                                          
3egf        1                                                                         0.00 b     Epidermal Growth Factor (Egf)
3gap  A     2     1.33272    9 -134;                                                  0.63 ab    Catabolite Gene Activator Protein
                         139 -189;                                                    1.00 a                                          
3gly        2     1.23122   51 -237;                                                  0.90 a     Glucoamylase-471 (1,4-alpha-d-glucan G
                           2 - 19;247 -429;                                           0.90 a                                          
3hhr  C     2     1.67892   35 -125;163 -166;                                         0.10 b     Human Growth Hormone
                         137 -160;174 -234;                                           0.00 b                                          
3hsc        4     1.59087   38 -135;
      0.52 ab 
                           7 - 28;141 -182;368 -379;
      0.53 ab 
                         193 -225;315 -353;
      0.38 ab 
                         230 -312;
      0.74 ab 
3il8        1                                                                         0.47 ab    Interleukin 8                         
3mdd  A     3c    1.45014   92 -233;                                                  0.37 ab    Medium Chain Acyl-CoA Dehydrogenase
                          18 - 90;244 -278;292 -392;                                  1.00 a                                          
                          (282 -287;)
3mon  A     1                                                                         0.00 b     Monellin                              
3sdh  A     2m    1.11478    3 -  8; 87 -111;129 -145;                                1.00 a     Hemoglobin I (Homodimer)                  1.00 a    
                          12 - 82;115 -124;                                           1.00 a                                          
3sgb  I     1                                                                         0.53 ab    Proteinase B From Streptomyces Griseus
4blm  A     2     1.30377   32 - 67;180 -195;230 -290;                                0.44 ab    Beta-Lactamase (Penicillinase)        
                          72 -154;201 -212;                                           0.93 a                                          
4cpa  I     1                                                                         0.00 b     Carboxypeptidase A=alpha= (Cox)
4enl        2     1.20405  129 -425;                                                  0.72 ab    Enolase (2-phospho-D-glycerate Hydrola
                           4 -125;                                                    0.68 ab                                         
4fxn        1                                                                         0.62 ab    Flavodoxin (Semiquinone Form)         
4gcr        2+    1.42345    2 - 84;                                                  0.00 b     Gammab  Crystallin
                          88 -158;                                                    0.13 b                                          
4gpb        3     1.45667   81 - 85;135 -159;191 -247;290 -481;813 -823;              0.63 ab    Glycogen Phosphorylase B
                         167 -178;497 -805;                                           0.81 a                                          
                          21 - 77; 95 -123;                                           1.00 a                                          
4rhv  1     2     1.37313   67 -255;                                                  0.14 b                                           
                          18 - 57;                                                    0.00 b                                          
4rhv  2     1                                                                         0.09 b     Rhinovirus 14 (HRV14)
4rhv  3     0*                 43-222;                                                0.18 b     Rhinovirus 14 (HRV14)
4rhv  4     1                                                                         1.00 a     Rhinovirus 14 (HRV14)
4sbv  A     3     1.24539   85 - 90;130 -186;223 -229;                                0.16 b     Southern Bean Mosaic Virus Coat Protein
                          98 -104;197 -219;                                           0.90 a                                          
                          67 - 80;109 -121;237 -250;                                  0.00 b                                          
4sgb  I     1                                                                         0.00 b     Serine Proteinase B
4tgf        2m    2.25260   38 - 46;                                                  0.00 b     Des-val==1==,Val==2==-transforming Gro    0.00 b    
                          20 - 33;                                                    0.00 b                                          
4xia  A     2c    1.15259   10 -337;379 -390;                                         0.82 a     D-Xylose Isomerase
                          (354 -372;)
5fd1        1                                                                         0.67 ab    Ferredoxin         
5p21        2m    1.02065   69 -164;                                                  0.74 ab    c-H-ras p21 Protein                       0.56 ab   
                           2 - 58;                                                    0.26 ab                                         
6fab  L     2     1.90025    4 -106;                                                  0.00 b     Antigen-binding Fragment Of The Murine
                         114 -210;                                                    0.15 b                                          
7api  B     1                                                                         0.00 b     Modified Alpha=1=-Antitrypsin
7ccp        3     1.32040   36 - 39;179 -240;                                         0.63 ab    Cytochrome C Peroxidase
                          16 - 32; 43 -118;                                           1.00 a                                          
                         151 -172;242 -271;                                           1.00 a                                          
7pti        1                                                                         0.36 ab    Bovine Pancreatic Trypsin Inhibitor
7rsa        2     1.27920    4 - 12; 51 - 74;106 -123;                                0.41 ab    Ribonuclease A       
                          25 - 47; 79 -104;                                           0.28 ab                                         
7znf        1                                                                         0.69 ab    Zinc-finger (Zfy-swap)
8abp        3+    1.46153  135 -141;169 -253;287 -300;                                0.52 ab    L-Arabinose-binding Protein
                           3 -108;256 -283;                                           0.64 ab                                         
                         110 -128;146 -162;                                           1.00 a                                          
8acn        3     1.52287   18 - 98;121 -208;236 -314;517 -518;                       0.64 ab    Aconitase
                         552 -751;                                                    0.53 ab                                         
                         109 -119;217 -228;321 -495;                                  0.70 ab                                         
8atc  A     3     1.40255  135 -290;                                                  0.66 ab    Aspartate Carbamoyltransferase
                          43 -129;                                                    0.58 ab                                         
                          17 - 32;292 -304;                                           1.00 a                                          
8cat  A     2     1.32035   10 - 16; 77 -147;213 -237;259 -364;                       0.38 ab    Catalase                              
                         160 -198;246 -255;440 -499;                                  1.00 a                                          
8fab  B     2     1.78801    3 -119;                                                  0.00 b     Fab Fragment From Human Immunoglobulin
                         128 -218;                                                    0.08 b                                          
8rxn  A     1                                                                         0.00 b     Rubredoxin                            
8tln  E     2     1.45014    4 -151; Thermolysin Complexed With Val-lys Dip           0.46 ab                                          
                         159 -312;                                                    0.89 a                                          
9rnt        1                                                                         0.36 ab    Ribonuclease T=1= Complex With Ca==2+=
9rub  A     4+    1.67664  143 -164;189 -191;227 -286;305 -392;                       0.61 ab    Ribulose-1,5-bisphosphate Carboxylase
                          14 -127;302 -303;                                           0.44 ab                                         
                         173 -181;198 -218;                                           0.86 a                                          
                         403 -439;                                                    1.00 a                                          
9wga  A     2     1.51234  103 -160;                                                  0.50 ab    Wheat Germ Agglutinin (Isolectin 2)   
                          17 - 74;                                                    0.50 ab                                         
_______________________________________________________________________________________________________________________________________________________

Ch. : Chain identifier

D   : disjoint factor (for details see Sowdhamini & Blundell, 1995).
 f

Helix content gives a measure of the secondary structural content. This is
the ratio between the number of residues in helices to the number of residues
in both helices and extended strands.
a: refers to helix-rich domains (helix content more than 0.80)
b: refers to strand-rich domains (helix content less than 0.20)
ab: refers to domains composed of helices and strands
    (helix content with intermediate values)

m  The domains corresponding to one of the clusters is not structurally compact; clusters are merged and considered as single-domain fold.

c  One of the clusters marked within brackets corresponds to a domain less than 25 residues; this small cluster is ignored.

*  The domain boundaries suggested by DIAL was quite different from graphical inspection; hence user-defined boundaries are used.

+  The domain boundaries suggested by DIAL have been altered slightly for structure comparison by SEA. 
(a) Residues 11-31 have been included in the second domain of 1apm (E chain).
(b) Residues 161-168 are considered part of the first domain of 1ars.
(c) 1cde is considered as a single domain fold.
(d) Residues 135 -295 (first domain) of 1chr (A chain) are considered part of the third domain.
(e) Residues 3-120 and 141-166 of 1ofv are alone considered as a single domain fold.
(f) Residues 119-122 of domain 1 of 1prs are considered part of the second domain.
(g) The second (residues 92 to 214 and 250 to 286) and fourth domains (residues 218 to 246) in 1tpl (A chain) are considered part of the third domain.
(h) 2ebn, 2hnq and 3dfr are considered as a single domain fold.
(i) Residues 159-169 are also considered part of the second domain in 4gcr.
(j) The third domain (residues 110-128 and 146-162) of 8abp is considered part of the first domain.
(k) Domains 3 and 4 of 9rub (A chain) are considered part of the first domain.


(Logo)

Section 10 Index

Index to Course Material