Last modified 12th April '95 © Birkbeck College 1995
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Alpha+Beta Topologies
This is where we collect together all those folds which include significant alpha and
beta secondary structural elements, but for which those elements are `mixed',
in the sense that they do NOT exhibit the
wound alpha-beta topology. This class of folds is
therefore referred to as alpha + beta
Thus we see that this class includes:-
- Bacterial (gif,
pdb) and
mammalian pancreatic (gif,
pdb) ribonucleases.
- Lysozome (gif,
pdb)
- Ubiquitin (gif,
pdb)
- Histidine-Carrier protein (gif,
pdb)
- Cysteine proteases such as papain and actinidin (gif,
pdb)
-
Zinc Metallo-proteases (gif,
pdb)
- SH2 domains (gif,
pdb)
- Protein G (prokaryotic Ig-binding) (gif,
pdb)
- FK506 binding protein (peptidyl-prolyl isomerase) (gif,
pdb)
- Ribonuclease-H (gif,
pdb)
- Carbonic anhydrase (gif,
pdb)
- Serine protease inhibitor (Serpins) (gif,
pdb)
- Thymidylate synthase (gif,
pdb)
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Alan Mills, Birkbeck College, Apr'95