Publications                                          Back to Dr Savva profile page

Unexpected correlations between gene expression and codon
usage bias from microarray data for the whole Escherichia coli
K-12 genome
dos Reis, M; Wernisch, L; and
Savva, R

(2003) Nucleic Acids Res., 31, pp.6976-6985

Crystal structure of the Escherichia coli dcm very-short-patch
DNA repair endonuclease bound to its reaction product-site
in a DNA superhelix
Bunting, KA; Roe, SM; Headley, A; Brown, T;
Savva, R and
Pearl, LH

(2003) Nucleic Acids Res., 31, pp.1633-1639

The mechanism of DNA repair by uracil-DNA glycosylase:
Studies using nucleotide analogues
Rösler, A; Panayotou, G; Hornby, DP; Barlow, T; Brown, T;
Pearl, LH;
Savva, R and Blackburn, GM
(2000) Nucleos. Nucleot. Nucleic Acids, 19, pp.1505-1516

Crystal structure of a thwarted mismatch glycosylase DNA
repair complex Barrett, TE; Scharer, OD;
Savva, R; Brown, T;
Jiricny, J; Verdine, GL and Pearl, LH

(1999) EMBO J., 19, pp.6599-6609

Structure of a DNA base-excision product resembling a cisplatin
inter-strand adduct
Barrett, TE;
Savva, R; Barlow, T; Brown, T; Jiricny, J and
Pearl, LH

(1998) Nature Struct. Biol., 5, pp.697-701

Crystal structure of a G:T/U mismatch-specific DNA glycosylase:
Mismatch recognition by complementary-strand interactions
Barrett, TE;
Savva, R; Panayotou, G; Barlow, T; Brown, T;
Jiricny, J and Pearl, LH

(1998) Cell, 92, pp.117-129

Direct measurement of the substrate preference of uracil-DNA

Panayotou, G; Brown, T; Barlow, T; Pearl, LH and Savva, R
(1998) J. Biol. Chem., 273, pp.45-50

Uracil-DNA glycosylase activities in hyperthermophilic

Koulis, A; Cowan, DA; Pearl, LH and Savva, R
(1996) FEMS Microbiol. Lett., 143, pp.267-271

The Problem With Pyrimidines
Pearl, LH and
Savva, R
(1996) Nature Struct. Biol., 3, pp.485-487

Nucleotide mimicry in the crystal-structure of the uracil-DNA
glycosylase - uracil glycosylase inhibitor protein complex
Savva, R and Pearl, LH
(1995) Nature Struct. Biol., 2, pp.752-757

DNA-Repair in 3 Dimensions
Pearl, LH and
Savva, R
(1995) Trends Bioch. Sci., 20, pp.421-426

Cloning and expression of the uracil-DNA glycosylase
inhibitor (UGI) from bacteriophage-PBS-1 and crystallization
of a uracil-DNA glycosylase-UGI complex
Savva, R and Pearl, LH
(1995) Prot.-Struct. Funct. Genet., 22, pp.287-289

The structural basis of specific base-excision repair by
uracil-DNA glycosylase

Savva, R; McAuley-Hecht, K; Brown, T and Pearl, L
(1995) Nature, 373, pp.487-493

Crystallization and preliminary X-ray analysis of the uracil-DNA
glycosylase DNA-repair enzyme from Herpes-Simplex Virus Type-1
Savva, R and Pearl, LH
(1993) J. Mol. Biol., 234, pp.910-912