Unexpected correlations between gene expression and codon
usage bias from microarray data for the whole Escherichia coli
K-12 genome
dos Reis, M; Wernisch, L; and Savva, R
(2003) Nucleic Acids Res., 31, pp.6976-6985
Crystal structure of the Escherichia coli dcm very-short-patch
DNA repair endonuclease bound to its reaction product-site
in a DNA superhelix
Bunting, KA; Roe, SM; Headley, A; Brown, T;Savva, R and
Pearl, LH
(2003) Nucleic Acids Res., 31, pp.1633-1639
The mechanism of DNA repair by uracil-DNA
glycosylase:
Studies using nucleotide analogues
Rösler, A; Panayotou, G; Hornby,
DP; Barlow, T; Brown, T;
Pearl, LH;
Savva, R and Blackburn, GM
(2000) Nucleos. Nucleot. Nucleic Acids, 19, pp.1505-1516
Crystal structure of a thwarted
mismatch glycosylase DNA
repair complex Barrett, TE; Scharer, OD;
Savva, R; Brown,
T;
Jiricny, J; Verdine, GL and Pearl, LH
(1999) EMBO J., 19,
pp.6599-6609
Structure of a DNA base-excision
product resembling a cisplatin
inter-strand adduct
Barrett, TE;
Savva, R; Barlow,
T; Brown, T; Jiricny, J and
Pearl, LH
(1998) Nature Struct. Biol.,
5, pp.697-701
Crystal structure of a G:T/U
mismatch-specific DNA glycosylase:
Mismatch recognition by complementary-strand
interactions
Barrett, TE; Savva, R;
Panayotou, G; Barlow, T; Brown, T;
Jiricny, J and Pearl, LH
(1998) Cell, 92,
pp.117-129
Direct measurement of the
substrate preference of uracil-DNA
glycosylase
Panayotou, G; Brown, T;
Barlow, T; Pearl, LH and Savva, R
(1998) J. Biol. Chem., 273,
pp.45-50
Uracil-DNA glycosylase activities
in hyperthermophilic
microorganisms
Koulis, A; Cowan, DA; Pearl,
LH and Savva, R
(1996) FEMS Microbiol. Lett.,
143, pp.267-271
The Problem With Pyrimidines
Pearl, LH and Savva, R
(1996) Nature Struct. Biol.,
3, pp.485-487
Nucleotide mimicry in the
crystal-structure of the uracil-DNA
glycosylase - uracil glycosylase inhibitor
protein complex
Savva, R
and Pearl, LH
(1995) Nature Struct. Biol.,
2, pp.752-757
DNA-Repair in 3 Dimensions
Pearl, LH and Savva, R
(1995) Trends Bioch. Sci.,
20, pp.421-426
Cloning and expression of
the uracil-DNA glycosylase
inhibitor (UGI) from bacteriophage-PBS-1 and
crystallization
of a uracil-DNA glycosylase-UGI complex
Savva,
R and Pearl, LH
(1995) Prot.-Struct. Funct.
Genet., 22, pp.287-289
The structural basis of specific
base-excision repair by
uracil-DNA glycosylase
Savva, R;
McAuley-Hecht, K; Brown, T and Pearl, L
(1995) Nature, 373, pp.487-493
Crystallization and preliminary
X-ray analysis of the uracil-DNA
glycosylase DNA-repair enzyme from Herpes-Simplex
Virus Type-1
Savva, R
and Pearl, LH
(1993) J. Mol. Biol., 234, pp.910-912