Protein Crystallography (PX)

Postgraduate Certificate

PX Syllabus

Section 1	Section 2	Section 3	Section 4	Section 5	Section 6	Section 7	Section 8
Section 9	Section 10	Section 11	Section 12	Section 13	Section 14	Section 15	Section 16

Section 15 - Validation

Introduction
Background
Steps and Strategy

Crystallographic Parameters

Coordinate Error - Luzzati Plot and SigmaA
Statistics - Reflections

Stereochemical Parameters

The Peptide Bond
Polypeptide Main Chain Torsion Angles
Ramachandran Plot
Side Chain Conformation
Ideal Stereochemistry and Restraints
Statistics - Geometry
Residue Environment
Hydrogen Bond
Hydrogen Bonds and Electron Density

Validation Programs and Checks