Section 12  Index

Index to Course Material

Prokaryotic Regulators

Many of the known activators and repressors of prokaryotic genes function as dimers.

• Selected DNA-binding Dimers

• The lac repressor , by Henry Brzeski, Dept of Bioscience and Biotechnology, University of Strathclyde

Eukaryotic Regulators

E.g. homeodomains such as

• Engrailed Homeodomain from fruit-fly 1hdd (154Kb) [Bbk|BNL|ExP|Waw|Hal]

  (Three diagrams of engrailed homeodomain 1 . . . 2 . . . 3 from SWISS-3DIMAGE)

• Antennapedia Homeodomain from fruit-fly (large file- NMR structures) 1ahd (3.0Mb) [Bbk|BNL|ExP|Waw|Hal]

• Homeodomain DNA Binding Proteins by Donovan Haines
  • Antennapedia Homeodomain
    1. Overview of the Structure
    2. Important DNA-protein Contacts
       • Detailed Helix III/IV Contacts
    3. Sequence and Genetic Aspects
  • Summary of conserved specifc homedomain protein-DNA interactions
  • References

Section 12  Index

Index to Course Material

Last updated 15th April '97