Distance learning: Principles of Protein Structure (PPS)

Postgraduate Certificate Syllabus

PPS Syllabus

Section 1	Section 2	Section 3	Section 4	Section 5	Section 6
Section 7	Section 8	Section 9	Section 10	Section 11	Section 12

Section 5 - Towards Tertiary Structure

5.1 Introduction
5.2 Supersecondary Structure (Motifs)

Beta hairpins I

Beta hairpins II

Tyrosine corners

Beta corners

Helix hairpins

Alpha-alpha corners

Helix-turn/loop-helix motif

Beta-alpha-beta motif

Greek key motif

5.3 Principles of Packing of Protein Secondary Structures

Helix-Helix Packing

Sheet-Sheet Packing

Beta-strand Packing in Alpha/Beta Barrels

Helix-Sheet Packing

5.4 Classification of Domain Folds

Mainly Alpha

Mainly Beta

Mainly Beta Proteins as Antiviral Drug Targets

Mixed Alpha-Beta

Small Proteins

5.5 Protein-Protein Interaction Domains
5.6 Protein-Ligand Interaction Domains
5.7 Modular Architecture
5.8 Tertiary Structure
5.9 Lens Proteins and Cataract: the gamma-crystallins
5.10 References