> Secondary Structure:
>
> Consecutive repeats of resides possessing similar main-chain
> conformations.
> Some might people like to include something about hydrogen bonds
> here, but I think this can cause more problems than it solves.
> Anyone disagree?
I would suggest as a definition of the secondary structure:
the local spatial arrangement of the polypeptide chain
because some segments which lacks regular structures still have
a secondary structure e.g beta-turns or omega loops
as to the hydrogen bonds, I totally aggree with Simon
> Tertiary Structure:
> Effectively the overall fold of a polypeptide chain. We could
> say it's a time-averaged model of the relative positions in
> three-dimensions of all the atoms in a polypeptide chain, but
> I'm sure someone can come up with something better than this.
this is a quite good definition
as to the quaternary structure, I would suggest:
the symetrical arrangement of subnits in a protein
anyone disaggrees?
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| Dr. Thierry MOREAU |
| Laboratoire d'Enzymologie et Chimie des Proteines |
| |
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