Part II. The Role of Phosphorylation



The chemical composition of the phosphoryl group confers upon the phosphorylated protein certain additional attributes which affects the structural, thermodynamic and kinetic properties of the phosphorylated protein.




Original work on protein phosphorylation focussed on the many enzymes of the carbohydrate, lipid, and amino acid metabolic pathways which were regulated by phosphorylation. Examination of the glucagon mediated signal transduction pathway of glycogen breakdown serves to illustrate the above points.

BACK
NEXT
TABLE OF CONTENTS