PPS 96 - People Directory


Principles Of Protein Structure 96 - The People

This page contains a list of the people associated with the January 1996 Internet Course on The Principles Of Protein Structure organized by Birkbeck College (UK) in collaboration with the Virtual School of Natural Sciences (VSNS) of the Globewide Network Academy (GNA)...with a little biographical information so we can get to know one another somewhat. At any given time this list should be considered to be incomplete for a number of reasons: it is not at all mandatory that you include yourself on this list, and I am also relatively slow at updating this portion of my contribution...please be patient! Thanks.

If you are part of the PPS 96 course and would like to be included in this list, please enter information in the PPS People Form. If your browser can't handle forms, please email the same information to schuman@bnlstb.bio.bnl.gov and we'll include it as soon as possible. There is also an official abbreviated list of pps 96 people by their assigned groups and countries. You can find people there and then look up MOO names here if they have entered their names in this list.

If you are interested in learning more about this course, please check out the course hypertree at Birkbeck College. This will provide lots of information on requirements, consultants, registration, and other general important facts.

I.C. Baianu, PhD
University of Illinois at Urbana
Email: i-baianu@uiuc.edu
PPS Status: Consultant
Biography: -
  1971-1974       Ph.D., Biophysics, Queen Elizabeth College, 
		  Department of Physics, University of London, UK

  1980-to present :     University of  Illinois atUrbana:
  1994-to present: Professor & Coordinator of AFC-NMR Facility,ACES College ,
FSHN Department: *  Biophysical Chemistry of  Proteins, Lipids, and
polysaccharides/;  Structural Biology;*  NMR of Protein Structure ,
Hydration and Dynamics;*  Experimental & Theoretical studies of Protein
Interactions;* Thermodynamic Linkage and Protein Activity ;*  Molecular
Dynamics of Concentrated Electrolyte  and Amino Acid Solutions; *  In vitro
and In vivo  NMR studies of Myocardium;*  NMR Analyses of Soybeans and
  1987-1993: Associate Professor (Research interests as stated above). 
  1982-1986: Assistant  Professor, (Research interests as stated above).
  1980-1982: Research Associate, School of Chemistry: Biophysical
Chemistry and NMR of proteins and membranes, with Professor H.S.Gutowsky,
Member of the National Academy of Sciences (USA).
  1979-1980: The LordRank Research Centre, Biophys. Dept.,High-Wycombe, 
Buckingamshire., UK, Senior Scientist: *  Biophysical Chemistry of Foods: *  
Pulsed NMR analyses of meat proteins, wheat gluten and grains;*  Magnetic 
Resonance Imaging of Wheat Grains and other seeds. 
  1977-1979: University of Cambridge, The Cavendish Laboratory, Cambridge, 
UK (Head of the Laboratory: Sir Neville Mott , Nobel Laureate in 1977): 
Science Research Council Research Fellow:  Structural and Magnetic Resonance  
studies of noncrystalline materials and relaxation processes, in collaboration 
with Dr. Collin Windsor, Fellow of The Royal Society.

  1995:    Elected Member, New York Academy of Sciences;
  1993: Elected Member, A.R. Academy of Arts and Sciences.
Simon Brocklehurst
Oxford Centre for Molecular Sciences, University of Oxford
Email: smb@bioch.ox.ac.uk
PPS Status: Advising Consultant
Biography: - Research Interests:

(Keywords: Protein Structure; Multidimensional NMR Spectroscopy; Computation; Modeling) Protein-protein interaction is a central aspect of biology. By using multidimensional NMR spectroscopy and novel computational approaches, both the three-dimensional structure of proteins and the intermolecular interactions in which they are involved, may be investigated at the atomic level. Particular emphasis is placed on the important problem of cytokine - receptor recognition which plays a key role in signal transduction. I am the author of NAOMI, a program system for studying many aspects of the three-dimensional structures of proteins.

Matthias Buck
Harvard University, Chemistry Department
Email: buck@tammy.harvard.edu
PPS Status: Consultant
Biography: - before 1984 school in Germany;1984-7 school in Edinburgh; 1987-90 Biochemistry (B.A.) Univ. of Cambridge, UK; 1990-94 Oxford Center for Molecular Sciences (D.Phil.), Univ. of Oxford, U.K. since then at Harvard Chemistry, USA. Interests: Dynamics and Folding of Proteins by NMR spectroscopy and molecular dynamics simulation.
Luis Candeias
Gray Laboratory Cancer Research Trust
BioMOO: luis
Email: candeias@graylab.ac.uk
PPS Status: Student
Biography: - My background is in physical chemistry, in particular kinetics and mechanisms of fast reactions. I graduated in Portugal (my home country) in Chemical Engineering. I did my PhD in Germany, at the Max-Planck Institut fuer Strahlenchemie, on DNA radiation damage. Currently I work at a cancer research laboratory where I apply my knowledge of physical chemistry to the design of future anti-cancer drugs. Through the way of activation of drugs to free-radicals, I became interested in peroxidase chemistry and from there came my interest in protein structure. If you want to know more about my research and general interests, logon my web page at http://www.graylab.ac.uk/usr/candeias/
Tony Day
San Francisco / Genencor Int.
BioMOO: tday
Email: tday@netcom.com
PPS Status: Student
Biography: - I am currently working as a research biochemist at the industrial biotechnology company, Genencor Int. Prior to this I did a post-doc in Alan Fershts Lab in Cambridge. I worked on the enzymology of a small ribonuclease, and on rubisco. I have a PhD in plant molecular biology from Imperial College, London, Where I worked on viral resistance by engineered antisense in Conrad Lichtenstein's Lab. I also hava M.Sc. from the University of British Columbia, where I worked glycosidases in Steve Withers group.
Marion Fennelly
Liverpool, John Moores
Email: marion@fennelly.u-net.com
PPS Status: Student
Biography: - I am a Biophysics undergraduate taking a year out.
Iddo Friedberg
Dept. of Biological Chemistry, Hebrew University, Israel
BioMOO: Iddo
Email: idoerg@shum.cc.huji.ac.il
PPS Status: Consultant
Biography: - Hi. I'm a graduate student in biology, doing research in Prof. J. Orly's lab on steroidogenic enzymes in mammalian female reproductive organs. Primarily I've set up a fluorescent-microscope based image-analysis system designed to quantitate minute amounts of protein in-situ. I did my BSc. in biology at the Hebrew University. Last year's course was a lot of fun, so I've decided to upgrade myself from student to consultant just so I could have an excuse to stick around. While my cell-cultures are growing in the incubator, and someone else is hogging the confocal microscope I spend my time maintaining the website of the institute, and (now) writing stuff for the PPS course
Kurt Giles
Weizmann Institute of Science
BioMOO: kurt
Email: kurt@sgjs6.weizmann.ac.il
PPS Status: Consultant
Biography: - I studied chemistry as an undergraduate at Oxford, then did my doctorate as a biochemist in the Pharmacology Departmant there. I worked on cholinesterases, specifically concerning their relationship to Alzheimer's disease. I'm now doing a post-doc at the Weizmann Institute in Israel on structure- function relationships of cholinesterases and the nicotinic acetylcholine receptor.
M. Jorge Guimarăes
DNAX Research Institute, 901 California Avenue, Palo Alto, CA 94304, USA.
BioMOO: jorge
Email: guimaraes@dnax.org and also mjorge@best.com
PPS Status: Student
Biography: - I am a Ph.D. student in haematopoietic development since the summer of 93. Before that I got my medical degree in Portugal (my home country), where I also did my medical internship. My research work is being conducted at DNAX Research Institute, Palo Alto, where I identified a number of novel genes which I am now trying to relate with haematopoietic development (Guimarăes et al. (1995) Development 121, 3335-3346). I became seriously involved in protein biochemistry and from there came my interest in structure and PPS96.
Vineet Gupta
University of Rochester, NY
BioMOO: Vineet
Email: vtga@uhura.cc.rochester.edu
PPS Status: Consultant
Biography: - I am a graduate student in the dept of Chemistry at the Univ. of Rochester. We work mostly with nucleic acids here, incorporating modified nucleosides into linear as well as small circular DNA/RNA chains.
Peter Hjelmstrom
Dept. of Medicine, Karolinska Institute, Sweden
Email: Peter.Hjelmstrom@medks.ki.se
PPS Status: Student
Biography: - I am an MD/PhD student currently interested in molecular modelling of HLA molecules and peptides associated with the autoimmune disease myasthenia gravis.
Agnes Hotz-Wagenblatt
German Cancer Research Center in Heidelberg, Germany
BioMOO: ahotz
Email: hotz-wagenblatt@dkfz-heidelberg.de
PPS Status: Student
Biography: - I am biologist, I have done some protein biochemistry work for my PhD, characterizing some protein kinase, learned some molecular biology in the States and have now a part time position in service. We offer people from DKFZ and outside sequence analysis programs and the sequence databases, training to use these tools, and help with any problems. Extension of these services in the direction of protein design is planned. The programs here run under UNIX, so I have experience with Unix, but I am not a co
Pierre Hubert
INSERM U.338, Strasbourg, France
BioMOO: PierreH
Email: hubert@neurochem.u-strasbg.fr
PPS Status: Student
Biography: - I am an MD turned biochemist/cell biologist. I am a "charge de recherche" within INSERM (the French biomedical research institution), and work in an INSERM lab in Strasbourg.

My current work deals with the role of transmembrane domains in the activation of tyrosine-kinase receptors. We are currently studying insulin receptors chimeric for their TM domain. We also use synthetic peptides with the sequence of TM domains. We work only with cultured mammalian cells, for signaling studies, or as a source for solubilized receptors. I also participate in the characterization of small antibacterial peptides derived from mammalian proteins, in collaboration with another group.

Graham S. Jackson
IACR-Long Ashton, University of Bristol
BioMOO: jacksong
Email: Graham.Jackson@bbsrc.ac.uk
PPS Status: Student
Biography: - I am currently employed as a postdoctoral research assistant within the Department of Chemistry at the University of Bristol. Most of my time is spent at the Institute of Arable Crops Research where we are attempting to determine the structure and function of of the biosynthetic enzymes of plant hormone biosynthesis. Research for my PhD was on spontaneous and chaperonin-assisted protein folding, which was also carried out at Bristol. My expertise is mainly in steady-state and transient kinetics with some molecular biology for light relief. I am hoping the course can assist me in getting to grips with computer technology and fill in some knowledge gaps on protein structure.
Andy Jennings
SmithKline Beecham, Harlow
BioMOO: AndyJ
Email: Andy_Jennings-1@sbphrd.com
PPS Status: Student
Biography: - I'm a medicinal chemist and have worked at SB for nearly 9 years. As well as this course, I am commencing a part-time PhD in Computational Chemistry this year. I will be looking at protein structures by family so I hope this course will assist me in this area. I am still working at the bench as an organic chemist so if anyone has any chemistry or general queries, feel free to e-mail me.
Dave Johnston
Natural History Museum, London
Email: daj@nhm.ac.uk
PPS Status: Student
Biography: - I work on Schistosoma, a parasitic blood fluke infecting some 200,000,000 people in tropical and sub-tropical areas. In collaboration with labs in Brazil and Egypt, we are involved in a gene discovery programme for S. mansoni using the expressed sequence tag approach. During the past year our lab has generated some 750 ESTs, approximately 65% of which have no match on the databases. I am hoping that the course will provide me with a better understanding of protein structure in general and facilitate our attempts to characterise/identify the proteins potentially coded by these EST sequences. Jobwise, I have special responsibility for developing parasite genome initiatives within the Museum and am secretary/database curator for the W.H.O. schistosoma genome initiative. Checkout http://woodland.bio.ic.ac.uk/fgn /parasite-genome/parasite-genome.html for info.
Silke Jonda
University of Frankfurt
Email: jonda@watson.rz.uni-frankfurt.de
PPS Status: Student
Biography: - I am an undergraduate, now in my seventh semester. Originally, I started with biology in Frankfurt, then took up physics as an additional subject. 1994/95 I was a visiting student at Trinity College Dublin, taking part in the biochemistry course. Currently, I am back in Frankfurt, not doing much at all... Talking about professional interests - as far as 'professional' is an appropriate expression - I am not quite sure what to write, but I hope that I will know better after this course. I have been using the Internet's basic facilities for two years, but I feel there is still much to learn.
Robert Kehoe
Daresbury Laboratory
BioMOO: Stretch
Email: rck@dlpx1.dl.ac.uk
PPS Status: Student
Biography: -
Sophia Kossida
Oxford University
BioMOO: SophiaK
Email: sophia.kossida@merton.ox.ac.uk
PPS Status: Consultant
Biography: - PhD student in Oxford University interested in Molecular Evolutioon and Bioinformatics
Ju-Seog Lee
University of Texas at Dallas
BioMOO: jslee
Email: jslee@utdallas.edu
PPS Status: Consultant
Biography: - I spent most of time to study ornithology and plant taxonomy in undergraduate (Kyunghee University in Korea). However, somehow I am studying molecular biology in University of Texas at Dallas (program in cell and molecular biology). Currently I am working on Src tyrosine kinase and its cellular substrates to understand src or its related kinases effect on cell growth control.
Jens Loesel
SmithKline Beecham Pharmaceuticals / Welwyn
Email: Jens_J_Loesel@sbphrd.com
PPS Status: Student
Biography: - I've started to work as a postdoctoral chemist just at the start of this year at SmithKline Beecham Phramaceuticals in Welwyn, this is approx. 30 km north of London. Before I started working here, I've studied chemistry in Frankfurt/Germany. My PhD was about Hydrogen Bonds in Crystals. I tried to solve two questions: 1. How can you define if there is an hydrogen bond or not? 2. Is there an easy measure for the strength of this bonds. I would say, I've answered both questions. If you now think, I should come from biochemistry, then you are totally wrong. I'm from inorganic chemistry. If you are interested to know more about me, e-mail me.
Jeffry D. Madura
University of South Alabama
Email: jmadura@jaguar1.usouthal.edu
PPS Status: Student
Biography: - I received my PhD in 1985 from Prof. William L. Jorgensen and did a post-doc with Prof. J. A. McCammon. I am now an Assistant Professor of Chemistry at the University of South Alabama. My research interests are in the development and application of theoretical and computational methods on molecules in solution. Currently I am studying the interactions of antifreeze proteins with ice and water. I have not had formal training in protein structure and this course filled that hole. Also I am interested in developing something like this for "Computational Chemistry for Undergraduates".
Aurora Martinez
Department of Biochemistry and Molecular Biology, University of Bergen, Norway
BioMOO: auroram
Email: aurora.martinez@pki.uib.no
PPS Status: Student
Biography: - I am an associate professor in Physical biochemistry and enzymology in the University of Bergen, where I came from Spain as a post-doc. in 1988. My research field is the structure-function relationships in metalloenzymes. At the moment I am working with the wild-type forms and several mutant forms of the recombinant human enzymes tyrosine hydroxylase and phenylalanine hydroxylase. I work with several biophysical techniques, mainly NMR and EPR spectroscopy. I investigate the role of the iron in the ox...
Alan Mills
Venus Internet Ltd
BioMOO: AlanM
Email: alan@venus.co.uk
PPS Status: Consultant (Adenine Group)
Biography: - Ex-physicist, Fellow at Birkbeck College, ageing hippy techno-freak, I was fortunate enough to have the opportunity last year to work with Peter Murray-Rust in running the PPS course for the first time round, and in doing so met several of the consultants and contributors (-: At Birkbeck I lectured on bioinformatics, and engaged in research in biomolecular structure, both modelling and crystallography. Now I also run my own company, Venus Internet Ltd building on the enthusiasm that infected me during PPS95. More info. on me is on my home page. Greetings to all my cyber-friends!
David Moss
Birkbeck College London
BioMOO: DavidM
Email: d.moss@mail.cryst.bbk.ac.uk
PPS Status: PPS96 Course Organiser
Biography: - I am Chariman of the Department of Crystallography at Birkbeck College. I am interested in software engineering. We are developing a bioinformatics class library. You may wish to help in this. Other research projects concern eye lens proteins, bacterial toxins and measurement and interpretation of protein X-ray diffuse scattering.
Salim Mottagui-Tabar
Stockholm University
BioMOO: Sam
Email: salim@mibi.su.se
PPS Status: Student
Biography: - I'm doing my Ph.D. in Microbiology, working on translation termination in bacteria. Expected to go on for a couple of more years. My interest in structures of proteins molecules is mainly due to almost total lack of available structures of molecules participating in the termination process. I love to keep in touch with the latest in the science world so as to be able to predict the future trends in science and opt for the right fields for my post Ph.D. work.
Shabir Najmudin
Crystallography, Birkbeck College, London
Email: s.najmudin@mail.cryst.bbk.ac.uk
PPS Status: Consultant
Biography: - I am currently helping with the PPS course. I am particularly interested in signal transduction proteins. I did my first degre, biochemistry, at Hertford College, Oxford, where I did a project with Louise Johnson. The title of my project was: 'The crystallographic study of metabolite analogues binding to phosphorylase b.' I completed my PhD at Birkbeck College uder the supervision of Tom Blundell, doing a structural analysis of the eye lens proteins, concentrating on the refinement of gamma B crystallin. At Glaxo-Wellcome, I did a refinement of two sets of penicillin- derived inhibitors complexed to HIV-1 protease in Alan Wonacott's group.
Catherine O'Malley
Boston Univiersity, MA USA
Email: CathyOM@aol.com
PPS Status: Student
Biography: - I am finishing a Ph.D. in pharmacology. My research project has implications for Alzheimer's disease.
Will Pitt
Birkbeck College
Email: w.pitt@mail.cryst.bbk.ac.uk
PPS Status: Consultant
Biography: - Current work: creating class library for bioinformatics and molecular modelling. At Birkbeck College, under the leadership of David Moss and Alan Bleasby. Post-doc: At Wyeth Research UK, working on the modelling of G-protein coupled receptors and ligands of these receptors PhD: Modelling of protein hydration sites. Produced the program AQUARIUS for the prediction of such sites. At Birkbeck, supervised by Julia Goodfellow.
Margherita Ruoppolo
Università di Napoli
BioMOO: Napoli
Email: gmarino@ds.unina.it
PPS Status: Student
Biography: - I am working in a biochemistry research group, involved in structural characterization of proteins. Our field of interest is mainly focused on protein folding, stability, post-translational modification, primary structure determination by mass-spectrometry and classical biochemistry, cloning and expression of proteins from extremophiles.
Paolo Scannapieco
Institute of Histology and Gen. Embriology
University of Padova, Padova ITALY
BioMOO: paolo
Email: onisto@civ.bio.unipd.it
PPS Status: Student
Biography: - I am an informatics and bioinformatics consultant at Institute of Histology and Gen. Embriology, University of Padova, Padova, Italy. In my lab we study the metalloproteases and their inhibitors involved in the invasion and metastasis processes. I am very interested to protein sequence analysis, protein structure and Internet.
Horst Joachim Schirra
Max-Planck-Institute for Biochemistry, Marinsried, Germany
Email: schirra@nmrvex.biochem.mpg.de
PPS Status: Student
Biography: - From 1988 to 1993 I studied Chemistry at the University of Frankfurt. During my Diploma Thesis in Frankfurt I tried to characterize the unfolded state of RNase T1 by NMR spectroscopy. By the end of 1993 I started my PhD thesis. My project is a collaboration between the NMR-group at the MPI for Biochemistry and the Institute for Molecular Biology and Biophysics at the ETH Zurich. Therefore I'm commuting very often between Munich and Zurich. My main interest in Biochemistry is the Problem of Protein Folding, which fascinates me since my fifth semester. My thesis also deals with this topic since I'm trying to solve the structure of a protein which is involved in protein folding by NMR spectroscopy.
Gayle Schulte
Pfizer Pharmaceutical Company
BioMOO: gayle_schulte
Email: schulteg@pfizer.com
PPS Status: Student
Biography: - I am a scientist at Pfizer involved in the structure elucidation of pharmacologically relevant macromolecules. The Protein Structure group as Pfizer has been in existence since 1993. I came by way of small molecule crystallography and spent a year in Prof. Paul Sigler's laboratory to learn what macromolecular crystallography was all about.
Gail I. Schuman
Brookhaven National Laboratory - Upton, NY
Department of Biology - Structural Biology
BioMOO: Ish (I think!)
Email: schuman@bnlstb.bio.bnl.gov
PPS Status: Consultant
Biography: - I work in the small-angle neutron scattering group with Dieter Schneider at the HFBR at BNL. I have MS degrees in both Physics (neutron) and Applied Mathematics. I also teach mathematics at a local community college. In my spare time (ha), I am also taking other courses (e.g., Biochemistry II this semester). I am the programmer/analyst for my group and help the PPS class in the area of world wide web and computer stuff! Hi!
Jacky Turner
Crystallography Department, Birkbeck College, London
BioMOO: jzt
Email: j.turner@mail.cryst.bbk.ac.uk
PPS Status: Coordinator/Tutor
Biography: - I am coordinating the PPS'96 course with John Walshaw - who does all the work - and David Moss, and acting as tutor to one of the student groups. I'm a lecturer in the Cryst. Dept. at Birkbeck where my research work is into structure and interactions in aqueous solutions, using neutron diffraction with isotope substitution and computer modelling.
John Walshaw
Crystallography, Birkbeck College
BioMOO: JohnW
Email: j.walshaw@mail.cryst.bbk.ac.uk
PPS Status: Coordinator
Biography: - I'm one of the coordinators of the new course, and manage the PPS Web pages. I came in about halfway through the original VSNS-PPS course in '95, and have also been involved in the project to put together a CD-Rom version. Before this, I completed my Ph.D. in Julia Goodfellow's Simulation Group in the same department, studying protein hydration using crystallographic data and Molecular Dynamics. I did my degree at Southampton University. At Birkbeck I have been the dept's "WebPerson" but will now be concentrating purely on the PPS course.
This page was last updated on 03/14/96 by Webmother