This page contains a list of the people associated with the January 1996 Internet Course on The Principles Of Protein Structure organized by Birkbeck College (UK) in collaboration with the Virtual School of Natural Sciences (VSNS) of the Globewide Network Academy (GNA)...with a little biographical information so we can get to know one another somewhat. At any given time this list should be considered to be incomplete for a number of reasons: it is not at all mandatory that you include yourself on this list, and I am also relatively slow at updating this portion of my contribution...please be patient! Thanks.
If you are part of the PPS 96 course and would like to be included in this list, please enter information in the PPS People Form. If your browser can't handle forms, please email the same information to schuman@bnlstb.bio.bnl.gov and we'll include it as soon as possible. There is also an official abbreviated list of pps 96 people by their assigned groups and countries. You can find people there and then look up MOO names here if they have entered their names in this list.
If you are interested in learning more about this course, please check out the course hypertree at Birkbeck College. This will provide lots of information on requirements, consultants, registration, and other general important facts.
EDUCATION : 1971-1974 Ph.D., Biophysics, Queen Elizabeth College, Department of Physics, University of London, UK PROFESSIONAL EXPERIENCE: 1980-to present : University of Illinois atUrbana: 1994-to present: Professor & Coordinator of AFC-NMR Facility,ACES College , FSHN Department: * Biophysical Chemistry of Proteins, Lipids, and polysaccharides/; Structural Biology;* NMR of Protein Structure , Hydration and Dynamics;* Experimental & Theoretical studies of Protein Interactions;* Thermodynamic Linkage and Protein Activity ;* Molecular Dynamics of Concentrated Electrolyte and Amino Acid Solutions; * In vitro and In vivo NMR studies of Myocardium;* NMR Analyses of Soybeans and Corn. 1987-1993: Associate Professor (Research interests as stated above). 1982-1986: Assistant Professor, (Research interests as stated above). 1980-1982: Research Associate, School of Chemistry: Biophysical Chemistry and NMR of proteins and membranes, with Professor H.S.Gutowsky, Member of the National Academy of Sciences (USA). 1979-1980: The LordRank Research Centre, Biophys. Dept.,High-Wycombe, Buckingamshire., UK, Senior Scientist: * Biophysical Chemistry of Foods: * Pulsed NMR analyses of meat proteins, wheat gluten and grains;* Magnetic Resonance Imaging of Wheat Grains and other seeds. 1977-1979: University of Cambridge, The Cavendish Laboratory, Cambridge, UK (Head of the Laboratory: Sir Neville Mott , Nobel Laureate in 1977): Science Research Council Research Fellow: Structural and Magnetic Resonance studies of noncrystalline materials and relaxation processes, in collaboration with Dr. Collin Windsor, Fellow of The Royal Society. HONORS AND AWARDS include: 1995: Elected Member, New York Academy of Sciences; 1993: Elected Member, A.R. Academy of Arts and Sciences.
(Keywords: Protein Structure; Multidimensional NMR Spectroscopy; Computation; Modeling) Protein-protein interaction is a central aspect of biology. By using multidimensional NMR spectroscopy and novel computational approaches, both the three-dimensional structure of proteins and the intermolecular interactions in which they are involved, may be investigated at the atomic level. Particular emphasis is placed on the important problem of cytokine - receptor recognition which plays a key role in signal transduction. I am the author of NAOMI, a program system for studying many aspects of the three-dimensional structures of proteins.
My current work deals with the role of transmembrane domains in the activation of tyrosine-kinase receptors. We are currently studying insulin receptors chimeric for their TM domain. We also use synthetic peptides with the sequence of TM domains. We work only with cultured mammalian cells, for signaling studies, or as a source for solubilized receptors. I also participate in the characterization of small antibacterial peptides derived from mammalian proteins, in collaboration with another group.