Re: Q: Helix dipoles

Simon Brocklehurst (
Fri, 15 Mar 1996 13:20:20 +0000 (GMT)

> So, I think that alpha-helix in this example has a greater dipole moment
> than the 3-10 helix.
> In the proposed approximation, the total dipole moment in an helix is the
> sum of the contributes coming from the dipoles present in each AA.
> The dipoles coming from the C-O and N-H in each AA are parallel to the axis
> of helix if this is an alpha elix.In 3-10 helix, C-O and N-H bonds of each
> AA form an angle with the axis, so just a componet of each dipole contribute
> to the final value.
Hi Cristina,
Thanks for taking the time to post an answer! You're absolutely
correct in what you say. Are there any other structural feature
of helices (i.e. apart from orientation of H-bonds relative to the
helical axis) that affect the "partial charges" at their terminii?

-- Simon
| ,_ o Simon M. Brocklehurst,
| / //\, Oxford Centre for Molecular Sciences, Department of Biochemistry,
| \>> | University of Oxford, Oxford, UK.
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