Re: Triple stranded DNA

Dr Alan Mills (
Tue, 13 Feb 1996 18:42:59 +0000 (GMT)


On Tue, 13 Feb 1996, William Pitt wrote:
> Question: is it possible that someone will ever design a quadruple (or
> more) stranded DNA structure?

Wouldn't that be the Holliday Junction?
Occurs naturally, but no structure has yet been done.

However, see pdb codes 196d and 1hjr

structures and

and the bibliographical references

gopher:// and

I suspect one, two, and three and four stranded structures need to be
allowed for in your designs, at least.

Oh, and don't forget single and double-stranded circular loops, with
varying degrees of supercoiling in the latter case.


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