"protein structures are selected because they are... stable
What kind of mutations are we talking about here?
Surely, in _general_ proteins are actually NOT stable against
mutations... and this would be _especially_ true of very
small proteins e.g. a 27-mer, wouldn't it?
Proteins are really only stable against _conservative_
mutations e.g. polar->polar, hydrophobic->hydrophobic.
Any comments anyone? What are the authors getting at?
| ,_ o Simon M. Brocklehurst,
| / //\, Oxford Centre for Molecular Sciences, Department of Biochemistry,
| \>> | University of Oxford, Oxford, UK.
| \\, E-mail: email@example.com | WWW: http://www.ocms.ox.ac.uk/~smb/