Gene Regulating Proteins

Index to Course Material Index to Section 12

Prokaryotic Regulators

• Selected DNA-binding Dimers

• The lac repressor , by Henry Brzeski, Dept of Bioscience and Biotechnology, University of Strathclyde

Eukaryotic Regulators

• Engrailed Homeodomain from fruit-fly 1hdd (154Kb) [Bbk|BNL|ExP|Waw|Hal]

  (Three diagrams of engrailed homeodomain 1 . . . 2 . . . 3 from SWISS-3DIMAGE)

• Antennapedia Homeodomain from fruit-fly (large file- NMR structures) 1ahd (3.0Mb) [Bbk|BNL|ExP|Waw|Hal]

• Homeodomain DNA Binding Proteins by Donovan Haines
  • Antennapedia Homeodomain
    1. Overview of the Structure
    2. Important DNA-protein Contacts
       • Detailed Helix III/IV Contacts
    3. Sequence and Genetic Aspects
  • Summary of conserved specifc homedomain protein-DNA interactions
  • References

Index to Course Material

Index to Section 12

Last updated 16th Jul '96